RBM11: A Drug Target / Disease Biomarker (G54033)
RBM11: A Drug Target / Disease Biomarker
RBM11 is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and liver. It is a member of the superfamily of RNA binding proteins (RBP), which are a group of proteins that interact with RNA molecules.
RBM11 is of particular interest as a potential drug target or biomarker because of its role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the most significant functions of RBM11 is its ability to interact with RNA molecules that are involved in the regulation of gene expression. This interaction is critical for the development and progression of many diseases, including cancer.
Research has shown that RBM11 can interact with several types of RNA molecules, including microRNAs (miRNAs) and long non-coding RNAs (lncNMs). These RNA molecules play important roles in regulating gene expression and can act as either negative or positive regulators depending on the context.
One of the ways that RBM11 interacts with miRNAs is through a process called RNA-protein interactions. RBM11 can bind to the target miRNA molecule and then work with it to either activate or inhibit its activity. This interaction between RBM11 and miRNAs is critical for the regulation of gene expression and can lead to the development of diseases.
Another way that RBM11 interacts with RNA molecules is through the formation of RNA-protein aggregates. These aggregates can form in the cytoplasm of cells and can interact with other proteins to affect their function.
Research has also shown that RBM11 can interact with lncNMs, which are long non-coding RNAs that can interact with RNA molecules to regulate gene expression. This interaction between RBM11 and lncNMs is important for the regulation of stem cell proliferation and the development of diseases such as cancer.
In addition to its role in interacting with RNA molecules, RBM11 is also involved in the regulation of cellular processes that are critical for the survival of cells. This includes the regulation of cell adhesion, the cytoskeleton, and the cell cycle.
One of the ways that RBM11 regulates cell adhesion is through its interaction with the protein cadherin. cadherin is a transmembrane protein that is involved in cell-cell adhesion and is composed of multiple domains, including an extracellular domain that is involved in cell adhesion. RBM11 can interact with cadherin and work with it to regulate cell adhesion, which is critical for the development and maintenance of tissues and organs.
RBM11 is also involved in the regulation of the cytoskeleton, which is the protein structure that organizes the cytoplasm of cells. This includes the regulation of microtubules, which are the basic building blocks of the cytoskeleton, and the regulation of the stability of the microtubules.
The regulation of the cell cycle is also an important function of RBM11. It is involved in the G1 phase of the cell cycle, which is the phase of growth and development when cells are preparing to enter cell division. During this phase, RBM11 can interact with the protein p21, which is a key regulator of the cell cycle.
In conclusion, RBM11 is a protein that is involved in a wide range of cellular processes that are critical for the survival of cells. Its interaction with RNA molecules, including miRNAs and lncNMs, is a key feature that allows it to regulate gene expression and play an important role in the development and progression of many diseases. Further research is needed to fully understand the functions of RBM11 and its potential as a drug target or biomarker.
Protein Name: RNA Binding Motif Protein 11
Functions: Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1
The "RBM11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RBM11 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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RBM12 | RBM12B | RBM14 | RBM14-RBM4 | RBM15 | RBM15-AS1 | RBM15B | RBM17 | RBM17P1 | RBM18 | RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45 | RBM46 | RBM47 | RBM48 | RBM48P1 | RBM4B | RBM5 | RBM5-AS1 | RBM6 | RBM7 | RBM8A | RBMS1 | RBMS1P1 | RBMS2 | RBMS2P1 | RBMS3 | RBMS3-AS3 | RBMX | RBMX2 | RBMX2P1 | RBMXL1 | RBMXL2 | RBMXL3 | RBMY1A1 | RBMY1B | RBMY1D | RBMY1F | RBMY1J | RBMY2EP | RBMY2FP | RBP1 | RBP2 | RBP3 | RBP4 | RBP5 | RBP7 | RBPJ | RBPJL | RBPJP2 | RBPMS | RBPMS-AS1 | RBPMS2 | RBSN | RBX1 | RC3H1 | RC3H2 | RCAN1 | RCAN2 | RCAN3 | RCAN3AS | RCBTB1 | RCBTB2 | RCC1 | RCC1L | RCC2 | RCCD1 | RCE1 | RCHY1 | RCL1 | RCN1 | RCN1P2 | RCN2 | RCN3 | RCOR1 | RCOR2 | RCOR3 | RCSD1 | RCVRN
