Target Name: RBM38
NCBI ID: G55544
Review Report on RBM38 Target / Biomarker Content of Review Report on RBM38 Target / Biomarker
RBM38
Other Name(s): RNA binding motif protein 38 | HSRNASEB | RNA-binding protein 38 (isoform c) | CLL-associated antigen KW-5 | RNA binding motif protein 38, transcript variant 1 | RNA-binding motif protein 38 | RBM38_HUMAN | RNA binding motif protein 38, transcript variant 3 | RNA-binding protein 38 (isoform a) | DJ800J21.2 | dJ800J21.2 | SEB4B | RNA-binding region-containing protein 1 | RNA-binding region (RNP1, RRM) containing 1 | SEB4D | RNPC1 | RNA binding region containing protein 1 | RNA-binding protein 38 | RBM38 variant 3 | ssDNA-binding protein SEB4 | RBM38 variant 1

RBM38: A Non-Coding RNA Protein with Significant Implications for Gene Expression and Disease

RNA binding motif (RBM) proteins are a family of non-coding RNAs that play a crucial role in regulating gene expression. RBM38 is a protein that belongs to the RBM family and is expressed in various tissues of the body. It is known to interact with RNA molecules and is involved in the regulation of gene expression.

RBM38 is a 21-kDa protein that is composed of 156 amino acid residues. It has a characteristic RBM domain that is present in the N-terminus of the protein. The RBM domain is responsible for the protein's ability to bind to RNA molecules.

RBM38 has been shown to interact with various RNA molecules, including microRNAs, ribosomal RNA (RRNA), and transfer RNA (tRNA). These interactions are important for the regulation of gene expression and for the proper function of the RNA machinery.

One of the unique features of RBM38 is its ability to form a stable complex with microRNAs. This interaction between RBM38 and microRNAs is important for the regulation of gene expression and for the development of various diseases, including cancer.

In addition to its role in regulating gene expression, RBM38 has also been shown to play a role in the regulation of protein synthesis. This is because RBM38 interacts with the protein translation machinery, which is responsible for the production of proteins from mRNA templates.

RBM38 has also been shown to play a role in the regulation of cellular processes, including cell division, apoptosis, and inflammation. This is because RBM38 interacts with various cellular signaling pathways, including the TGF-β pathway and the NF-kappa-B pathway.

The potential drug targets for RBM38 are numerous. One of the main targets for RBM38 is the regulation of cancer progression. RBM38 has been shown to play a role in the regulation of cancer cell proliferation and has been shown to be involved in the development of various types of cancer.

Another potential drug target for RBM38 is the regulation of autoimmune diseases. RBM38 has been shown to play a role in the regulation of immune cell function and has been implicated in the development of autoimmune diseases.

In addition to its potential drug targets, RBM38 also has potential as a biomarker for various diseases. For example, RBM38 has been shown to be involved in the regulation of gene expression in various diseases, including cancer, and has been used as a potential biomarker for these diseases.

Overall, RBM38 is a protein that has significant implications for the regulation of gene expression and has the potential to be a drug target or biomarker for various diseases. Further research is needed to fully understand the role of RBM38 in cellular processes and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: RNA Binding Motif Protein 38

Functions: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation

The "RBM38 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RBM38 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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