Target Name: RB1CC1
NCBI ID: G9821
Review Report on RB1CC1 Target / Biomarker Content of Review Report on RB1CC1 Target / Biomarker
RB1CC1
Other Name(s): FIP200 | OTTHUMP00000226291 | ATG17 | RB1 inducible coiled-coil 1, transcript variant 1 | RB1-inducible coiled-coil protein 1 | RB1-inducible coiled-coil protein 1 (isoform 1) | FAK family kinase-interacting protein of 200 kDa | RB1CC1 variant 1 | KIAA0203 | phosphatase 1, regulatory subunit 131 | PPP1R131 | RBCC1_HUMAN | 200 kDa FAK family kinase-interacting protein | RBICC | OTTHUMP00000226290 | RB1 inducible coiled-coil 1 | CC1

RB1CC1: Key Regulator of The AP-1 Gene

RB1CC1 (FIP200), also known as FIP-伪 chain, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the inevitable protein (AP-1) gene, which is responsible for the production of collagen.Collagen is a protein that is found in the skin, hair, nails, and bones, among other things. It helps to provide structure and support to these tissues.

RB1CC1 is a non-coding RNA molecule that plays a critical role in the regulation of the AP-1 gene. It is a negative regulator of the AP-1 gene, which means that it works to prevent the gene from being expressed.

One of the functions of RB1CC1 is to interact with the AP-1 gene. This interaction occurs through the AP-1 gene's upstream region, which is known as the \"intron.\" The intron is the region of the AP-1 gene that contains the regions that are not being translated into protein.

RB1CC1 is able to bind to the intron of the AP-1 gene because of its specific sequence. This interaction between RB1CC1 and the AP-1 gene is important for the regulation of the AP-1 gene.

Another function of RB1CC1 is to regulate the production of AP-1 protein. When the AP-1 gene is expressed, RB1CC1 helps to ensure that it is properly translated into protein.

In addition to its role in regulating the AP-1 gene, RB1CC1 is also involved in the regulation of other genes. For example, it has been shown to play a role in the regulation of the Notch gene, which is involved in the development and maintenance of tissues such as bones and teeth.

RB1CC1 is also expressed in various tissues throughout the body, including the skin, hair, and nails. This makes it an attractive drug target for researchers because it is potential to be used to treat a variety of conditions that are caused by the regulation of the AP-1 gene or the Notch gene.

In conclusion, RB1CC1 is a non-coding RNA molecule that plays a critical role in the regulation of the inevitable protein (AP-1) gene. It is a negative regulator of the AP-1 gene and is involved in the regulation of the production of AP-1 protein. It is also expressed in various tissues throughout the body, which makes it an attractive drug target for researchers. Further research is needed to fully understand the role of RB1CC1 in the regulation of AP-1 gene and its potential uses in treating various diseases.

Protein Name: RB1 Inducible Coiled-coil 1

Functions: Involved in autophagy (PubMed:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (By similarity). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (By similarity). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (By similarity). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007). Plays a crucial role in muscular differentiation (PubMed:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity)

The "RB1CC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RB1CC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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