Target Name: RASGEF1A
NCBI ID: G221002
Review Report on RASGEF1A Target / Biomarker Content of Review Report on RASGEF1A Target / Biomarker
RASGEF1A
Other Name(s): RasGEF domain family member 1A, transcript variant 1 | RASGEF1A variant 1 | RasGEF domain family member 1A | Ras-GEF domain-containing family member 1A | RASGEF1A variant 2 | CG4853 gene product | Ras-GEF domain-containing family member 1A (isoform 1) | Ras-GEF domain-containing family member 1A (isoform 2) | RGF1A_HUMAN | CG4853 | RasGEF domain family member 1A, transcript variant 2

Regulation of GPR17 By RasGEF1A: Implications for Cell Signaling

The RasGEF1A gene is a member of the Ras gene family, which is involved in cell signaling pathways. It is a 21-kDa protein that is expressed in various tissues, including the brain, heart, and kidneys. The primary function of RasGEF1A is to regulate the activity of the G protein-coupled receptor GPR17, which is a key regulator of cell signaling.

GPR17 is a transmembrane protein that is involved in various physiological processes in the body, including sensory perception, neurotransmitter signaling, and cell survival. It is composed of a extracellular domain, a transmembrane domain, and an intracellular domain. The transmembrane domain of GPR17 is the region of the protein that is involved in its signaling functions, and it is composed of four transmembrane spanning domains: 伪2, 尾2, 纬2, and 未2.

The RasGEF1A gene is located on chromosome 16, and it is a single exon gene. It has a length of 114 amino acids, and its protein has a molecular mass of 19.1 kDa. The RasGEF1A gene is expressed in various tissues of the body, including the brain, heart, and kidneys. It is primarily expressed in the brain, where it is involved in the regulation of neuronal communication and behavior.

The primary function of RasGEF1A is to regulate the activity of the G protein-coupled receptor GPR17. GPR17 is a transmembrane protein that is involved in various physiological processes in the body, including sensory perception, neurotransmitter signaling, and cell survival. It is composed of a extracellular domain, a transmembrane domain, and an intracellular domain. The transmembrane domain of GPR17 is the region of the protein that is involved in its signaling functions, and it is composed of four transmembrane spanning domains: 伪2, 尾2, 纬2, and 未2.

The RasGEF1A gene is located on chromosome 16, and it is a single exon gene. It has a length of 114 amino acids, and its protein has a molecular mass of 19.1 kDa. The RasGEF1A gene is expressed in various tissues of the body, including the brain, heart, and kidneys. It is primarily expressed in the brain, where it is involved in the regulation of neuronal communication and behavior.

Studies have shown that RasGEF1A is involved in various physiological processes in the body, including neuronal communication and behavior. It has been shown to regulate the migration and survival of neurons, and to play a role in the regulation of neurotransmitter signaling. Additionally, studies have shown that RasGEF1A is involved in the regulation of cell signaling pathways, including the regulation of cell adhesion and the regulation of cell proliferation.

In conclusion, the RasGEF1A gene is a member of the Ras gene family and is involved in the regulation of various physiological processes in the body. It is primarily expressed in the brain and is involved in the regulation of neuronal communication and behavior. The primary function of RasGEF1A is to regulate the activity of the G protein-coupled receptor GPR17, which is a key regulator of cell signaling. Further research is needed to fully understand the role of RasGEF1A in the regulation of cellular processes and its potential as a drug target.

Protein Name: RasGEF Domain Family Member 1A

Functions: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration

The "RASGEF1A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RASGEF1A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RASGEF1B | RASGEF1C | RASGRF1 | RASGRF2 | RASGRP1 | RASGRP2 | RASGRP3 | RASGRP4 | RASIP1 | RASL10A | RASL10B | RASL11A | RASL11B | RASL12 | RASSF1 | RASSF10 | RASSF2 | RASSF3 | RASSF4 | RASSF5 | RASSF6 | RASSF7 | RASSF8 | RASSF8-AS1 | RASSF9 | RAVER1 | RAVER2 | RAX | RAX2 | RB1 | RB1-DT | RB1CC1 | RBAK | RBAK-RBAKDN | RBAKDN | RBBP4 | RBBP4P2 | RBBP4P6 | RBBP5 | RBBP6 | RBBP7 | RBBP8 | RBBP8NL | RBBP9 | RBCK1 | RBFA | RBFOX1 | RBFOX2 | RBFOX3 | RBIS | RBKS | RBL1 | RBL2 | RBM10 | RBM11 | RBM12 | RBM12B | RBM14 | RBM14-RBM4 | RBM15 | RBM15-AS1 | RBM15B | RBM17 | RBM17P1 | RBM18 | RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45 | RBM46 | RBM47 | RBM48 | RBM48P1 | RBM4B | RBM5 | RBM5-AS1 | RBM6 | RBM7 | RBM8A | RBMS1 | RBMS1P1