Target Name: RBM18
NCBI ID: G92400
Review Report on RBM18 Target / Biomarker Content of Review Report on RBM18 Target / Biomarker
RBM18
Other Name(s): RNA binding motif protein 18 | RNA-binding motif protein 18 | RNA binding motif protein 18, transcript variant 1 | Probable RNA-binding protein 18 | RBM18_HUMAN | RBM18 variant 1

Understanding The Role of RBM18 in Stem Cell Biology and Metabolism

RNA binding motif (RBM) proteins are a family of non-protein coding RNAs that play a crucial role in various cellular processes. These proteins are known to interact with RNA molecules and are involved in the regulation of gene expression. One of the well- known RBM proteins is RBM18, which is a protein that is expressed in various tissues and cell types. While the exact function of RBM18 is not yet well understood, research has shown that it plays a significant role in the regulation of stem cell proliferation and differentiation . As a result, RBM18 has been identified as a potential drug target and biomarker.

The RBM18 protein is a member of the RBM family, which includes several well-known proteins, such as RBM1, RBM2, RBM3, and RBM4. These proteins share a conserved motif, which consists of a nucleotide-binding oligomerization (NBO) domain and a carboxylic acid-containing domain. The NBO domain is responsible for the protein's ability to interact with RNA, while the carboxylic acid-containing domain is involved in the protein's stability and localization.

RBM18 is a non-coding RNA molecule that is predominantly expressed in the brain and spinal cord. It has been shown to be involved in the regulation of stem cell proliferation and differentiation. Stem cells are a type of cell that have the ability to develop into any type of cell in the body. They are a key source of tissue repair and regeneration and have the potential to be used for the development of personalized therapies. The regulation of stem cell proliferation and differentiation is critical for the maintenance of tissue homeostasis and the development of a healthy organism.

RBM18 has been shown to play a significant role in this process. Studies have shown that RBM18 is involved in the regulation of stem cell self-renewal and proliferation. It has been shown to promote the growth and survival of mouse embryonic stem cells and to inhibit the differentiation of these cells into teratogenic cell types. These findings suggest that RBM18 may be a useful drug target or biomarker for the treatment of various diseases, such as cancer, neurodegenerative diseases, and developmental disorders.

In addition to its role in stem cell biology, RBM18 has also been shown to be involved in the regulation of cell survival and metabolism. Studies have shown that RBM18 is involved in the regulation of cell apoptosis, which is a natural mechanism for cell death that is essential for the maintenance of tissue homeostasis. In addition, RBM18 has been shown to be involved in the regulation of cell metabolism, including the regulation of protein synthesis and the detoxification of harmful substances.

Given its involvement in the regulation of stem cell biology and metabolism, RBM18 is an attractive target for drug development. The use of small molecules or antibodies to inhibit or activate RBM18's activity could provide new therapeutic options for the treatment of various diseases. For example, RBM18 has been shown to be involved in the regulation of cell apoptosis, which could make it a potential target for the treatment of neurodegenerative diseases. Additionally, the regulation of stem cell proliferation and differentiation by RBM18 may make it a potential target for the treatment of cancer.

In conclusion, RBM18 is a non-protein coding RNA molecule that is expressed in various tissues and cell types. Its function is not yet well understood, but research has shown that it plays a significant role in the regulation of stem cell proliferation and differentiation. As a result, RBM18 has been identified as a potential drug target and biomarker, with potential for the treatment of various diseases. Further research is needed to fully understand the function of RBM18 and its potential as a therapeutic agent.

Protein Name: RNA Binding Motif Protein 18

The "RBM18 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RBM18 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45 | RBM46 | RBM47 | RBM48 | RBM48P1 | RBM4B | RBM5 | RBM5-AS1 | RBM6 | RBM7 | RBM8A | RBMS1 | RBMS1P1 | RBMS2 | RBMS2P1 | RBMS3 | RBMS3-AS3 | RBMX | RBMX2 | RBMX2P1 | RBMXL1 | RBMXL2 | RBMXL3 | RBMY1A1 | RBMY1B | RBMY1D | RBMY1F | RBMY1J | RBMY2EP | RBMY2FP | RBP1 | RBP2 | RBP3 | RBP4 | RBP5 | RBP7 | RBPJ | RBPJL | RBPJP2 | RBPMS | RBPMS-AS1 | RBPMS2 | RBSN | RBX1 | RC3H1 | RC3H2 | RCAN1 | RCAN2 | RCAN3 | RCAN3AS | RCBTB1 | RCBTB2 | RCC1 | RCC1L | RCC2 | RCCD1 | RCE1 | RCHY1 | RCL1 | RCN1 | RCN1P2 | RCN2 | RCN3 | RCOR1 | RCOR2 | RCOR3 | RCSD1 | RCVRN | RD3 | RD3L | RDH10 | RDH11 | RDH12 | RDH13 | RDH14 | RDH16 | RDH5 | RDH8