Target Name: MFSD2B
NCBI ID: G388931
Review Report on MFSD2B Target / Biomarker Content of Review Report on MFSD2B Target / Biomarker
MFSD2B
Other Name(s): Major facilitator superfamily domain containing 2B | SLC59A2 | MFSD2 lysolipid transporter B, sphingolipid | Major facilitator superfamily domain-containing protein 2B | hMfsd2b | MFS2B_HUMAN | Sphingosine-1-phosphate transporter MFSD2B | sphingosine 1-phosphate transporter | S1P transporter | major facilitator superfamily domain-containing protein 2b | major facilitator superfamily domain containing 2B

MFSD2B: A Protein Involved in Various Cellular Processes and Potential Drug Target

The Major Facilitator Superfamily Domain Containing 2B (MFSD2B) is a protein that plays a crucial role in various cellular processes. It is a family of transmembrane proteins that are characterized by the presence of a catalytic center in the cytoplasmic side of the membrane. MFSD2B proteins are involved in a wide range of cellular processes, including intracellular signaling, protein-protein interactions, and intracellular transport.

One of the key functions of MFSD2B proteins is their ability to catalyze a variety of chemical reactions. These reactions include the transfer of electrons, the formation of bonds, and the breaking of bonds. MFSD2B proteins are also involved in the regulation of various cellular processes, including cell signaling, cell growth, and apoptosis.

MFSD2B proteins have also been shown to play a role in the development and progression of various diseases. For example, MFSD2B has been implicated in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the development of cancer, including breast cancer.

Due to its involvement in a wide range of cellular processes, MFSD2B has been identified as a potential drug target. Researchers are currently working to develop drugs that can inhibit the activity of MFSD2B proteins in order to treat various diseases. These drugs may be used to treat neurodegenerative diseases, cancer, and other conditions that are caused by the over- activity of MFSD2B proteins.

In addition to its potential as a drug target, MFSD2B is also an attractive biomarker for certain diseases. The over- activity of MFSD2B proteins has been implicated in the development of various diseases, including neurodegenerative diseases. By measuring the activity of MFSD2B proteins, researchers can gain insights into the underlying causes of these diseases and develop more effective treatments.

Overall, MFSD2B is a protein that plays a crucial role in various cellular processes. It is also a potential drug target and biomarker for a wide range of diseases. Further research is needed to fully understand the role of MFSD2B in cellular processes and its potential as a drug and biomarker.

Protein Name: MFSD2 Lysolipid Transporter B, Sphingolipid

Functions: Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets (PubMed:29045386). Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Sphingosine-1-phosphate export from platelets is required for platelet aggregation and thrombus formation (By similarity). Mediates the export of different sphingosine-1-phosphate (S1P) species, including S1P(d18:0) (sphinganine 1-phosphate), S1P (d18:1) (sphing-4-enine 1-phosphate) and S1P (d18:2) (sphinga-4E,14Z-dienine-1-phosphate) (Probable). Release of sphingosine-1-phosphate is facilitated by a proton gradient (By similarity). In contrast, cations, such as sodium, are not required to drive sphingosine-1-phosphate transport (Probable). In addition to export, also able to mediate S1P import (By similarity). Does not transport lysophosphatidylcholine (LPC) (Probable)

The "MFSD2B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MFSD2B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MFSD3 | MFSD4A | MFSD4A-AS1 | MFSD4B | MFSD4B-DT | MFSD5 | MFSD6 | MFSD6L | MFSD8 | MFSD9 | MGA | MGAM | MGAM2 | MGARP | MGAT1 | MGAT2 | MGAT3 | MGAT3-AS1 | MGAT4A | MGAT4B | MGAT4C | MGAT4D | MGAT4EP | MGAT4FP | MGAT5 | MGAT5B | MGC12916 | MGC15885 | MGC16025 | MGC16275 | MGC27382 | MGC2889 | MGC32805 | MGC34796 | MGC4859 | MGC70870 | MGLL | MGME1 | MGMT | MGP | MGRN1 | MGST1 | MGST2 | MGST3 | MHRT | MIA | MIA-RAB4B | MIA2 | MIA3 | MIAT | MIATNB | MIB1 | MIB2 | MICA | MICA-AS1 | MICAL1 | MICAL2 | MICAL3 | MICALCL | MICALL1 | MICALL2 | MICB | MICB-DT | MICC | MICD | MICOS10 | MICOS10-NBL1 | MICOS10P1 | MICOS13 | Microfilament-associated triple complex | MicroRNA 1273d | MicroRNA 1273f | MicroRNA 1273g | MicroRNA 3607 | MicroRNA 3653 | MicroRNA 3656 | MicroRNA 4417 | MicroRNA 4419a | MicroRNA 4459 | MicroRNA 4461 | MicroRNA 4532 | MicroRNA 4792 | MicroRNA 5095 | MicroRNA 5096 | MicroRNA 6087 | MicroRNA 6723 | MicroRNA 7641-1 | MicroRNA 7641-2 | Microtubule-Associated Protein | MICU1 | MICU2 | MICU3 | MID1 | MID1IP1 | MID1IP1-AS1 | MID2 | MIDEAS | MIDEAS-AS1 | MIDN | MIEF1