Target Name: MFF
NCBI ID: G56947
Review Report on MFF Target / Biomarker Content of Review Report on MFF Target / Biomarker
MFF
Other Name(s): GL004 | C2orf33 | mitochondrial fission factor | MFF_HUMAN | EMPF2 | Mitochondrial fission factor | Mitochondrial fission factor, transcript variant 2 | DKFZp666J168 | OTTHUMP00000203987 | MFF variant 2 | MGC110913 | OTTHUMP00000203989 | Mitochondrial fission factor (isoform a) | OTTHUMP00000164235

MFFs as Potential Drug Targets

MFF, or microRNA-functional fragment, is a type of non-coding RNA molecule that plays a critical role in regulating gene expression in various organisms, including humans. MFFs are derived from microRNAs, which are small non-coding RNAs that are derived from RNA polymerase II intron-containing transcription units.

MFFs have been identified as potential drug targets in the medical field due to their involvement in various diseases, including cancer, neurodegenerative diseases, and developmental disorders. They are also widely used as biomarkers for diagnostic purposes, such as monitoring disease progression and evaluating the effectiveness of treatments.

One of the key factors contributing to MFF's potential as a drug target is its dynamic nature. MFFs are constantly being produced and degraded in the body, which allows them to fluctuate levels and be easily modified by various factors, such as drug treatments. This dynamic nature allows MFFs to be targeted by small molecules, which can alter their stability or activity.

Another important factor is the specificity of MFFs as drug targets. Unlike many other biomarkers, MFFs are not specific to a particular disease or condition, but rather are potential targets for a wide range of diseases. This means that MFFs can be used as a valuable tool for the development of new treatments for a variety of diseases.

MFFs have also been shown to be involved in various signaling pathways that are involved in disease progression. For example, MFFs have been shown to be involved in the regulation of cell proliferation, which is a key factor in the development of many diseases, including cancer . Additionally, MFFs have been shown to be involved in the regulation of cell apoptosis, which is a natural mechanism that helps cells remove damaged or unnecessary proteins, and is important for maintaining tissue homeostasis.

MFFs have also been shown to be involved in the regulation of various cellular processes that are important for maintaining cellular health and homeostasis. For example, MFFs have been shown to be involved in the regulation of cell migration, which is important for the development and maintenance of tissues and organs. Additionally, MFFs have been shown to be involved in the regulation of cell adhesion, which is important for the formation and maintenance of tissues and organs.

In conclusion, MFF is a potential drug target and biomarker that has been identified in various diseases. Its dynamic nature and specificity make it an attractive target for small molecule-based therapies. Further research is needed to fully understand the role of MFFs in disease progression and the development of new treatments.

Protein Name: Mitochondrial Fission Factor

Functions: Plays a role in mitochondrial and peroxisomal fission (PubMed:18353969, PubMed:23530241, PubMed:24196833). Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (PubMed:23530241). May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles (By similarity)

The "MFF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MFF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MFF-DT | MFGE8 | MFHAS1 | MFN1 | MFN2 | MFNG | MFRP | MFSD1 | MFSD10 | MFSD11 | MFSD12 | MFSD13A | MFSD14A | MFSD14B | MFSD14CP | MFSD2A | MFSD2B | MFSD3 | MFSD4A | MFSD4A-AS1 | MFSD4B | MFSD4B-DT | MFSD5 | MFSD6 | MFSD6L | MFSD8 | MFSD9 | MGA | MGAM | MGAM2 | MGARP | MGAT1 | MGAT2 | MGAT3 | MGAT3-AS1 | MGAT4A | MGAT4B | MGAT4C | MGAT4D | MGAT4EP | MGAT4FP | MGAT5 | MGAT5B | MGC12916 | MGC15885 | MGC16025 | MGC16275 | MGC27382 | MGC2889 | MGC32805 | MGC34796 | MGC4859 | MGC70870 | MGLL | MGME1 | MGMT | MGP | MGRN1 | MGST1 | MGST2 | MGST3 | MHRT | MIA | MIA-RAB4B | MIA2 | MIA3 | MIAT | MIATNB | MIB1 | MIB2 | MICA | MICA-AS1 | MICAL1 | MICAL2 | MICAL3 | MICALCL | MICALL1 | MICALL2 | MICB | MICB-DT | MICC | MICD | MICOS10 | MICOS10-NBL1 | MICOS10P1 | MICOS13 | Microfilament-associated triple complex | MicroRNA 1273d | MicroRNA 1273f | MicroRNA 1273g | MicroRNA 3607 | MicroRNA 3653 | MicroRNA 3656 | MicroRNA 4417 | MicroRNA 4419a | MicroRNA 4459 | MicroRNA 4461 | MicroRNA 4532 | MicroRNA 4792 | MicroRNA 5095