Target Name: MFGE8
NCBI ID: G4240
Review Report on MFGE8 Target / Biomarker Content of Review Report on MFGE8 Target / Biomarker
MFGE8
Other Name(s): HMFG | Milk fat globule EGF and factor V/VIII domain containing, transcript variant 1 | Lactadherin short form | MFGM_HUMAN | SED1 | Sperm associated antigen 10 | BA46 | Sperm surface protein hP47 | ICTE1030 | Medin | Lactadherin | MFGM | Breast epithelial antigen BA46 | sperm associated antigen 10 | EDIL1 | sperm surface protein hP47 | MFGE8 variant 1 | OAcGD3S | O-acetyl disialoganglioside synthase | milk fat globule EGF and factor V/VIII domain containing | hP47 | MFG-E8 | milk fat globule-EGF factor 8 protein | HsT19888 | Milk fat globule-EGF factor 8 protein | SPAG10 | breast epithelial antigen BA46 | Milk fat globule-EGF factor 8 | Lactadherin (isoform a) | medin

MFGE8: A Protein Involved in Cell Signaling and Adhesion in Various Tissues

MFGE8 (Mesothelin- Associated Glycoprotein-Expronized 8) is a protein that is expressed in various tissues and cells in the human body. It is a member of the mesothelin family, which is a group of proteins that are involved in cell signaling and adhesion. MFGE8 is unique among mesothelin proteins because it is expressed in the placenta, which is a vital organ that plays a critical role in the development and maintenance of fetal tissue.

One of the main functions of MFGE8 is its role in cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. MFGE8 helps to regulate cell adhesion by participating in a signaling pathway that involves the interaction between cells and the extracellular matrix (ECM).

MFGE8 is also involved in the regulation of cell proliferation. It has been shown to play a role in the control of cell proliferation in various tissues, including the placenta. By regulating cell proliferation, MFGE8 may be involved in the development and maintenance of tissues and organs.

In addition to its role in cell adhesion and proliferation, MFGE8 is also involved in the regulation of cell death. Cell death, also known as apoptosis, is an essential process that helps to remove damaged or dysfunctional cells from the body. MFGE8 has been shown to play a role in the regulation of cell death in various tissues, including the brain.

MFGE8 is also a potential drug target. Its involvement in various biological processes makes it an attractive target for researchers to study and develop new treatments for various diseases. For example, MFGE8 has been shown to be involved in the development of cancer, and researchers are currently studying its potential as a drug target for this disease.

In conclusion, MFGE8 is a unique and important protein that plays a critical role in various tissues and cells in the human body. Its involvement in cell adhesion, proliferation, and death makes it an attractive target for researchers to study and develop new treatments for various diseases. As research continues to advance, it is likely that we will learn more about the role of MFGE8 in biology and its potential as a drug target.

Protein Name: Milk Fat Globule EGF And Factor V/VIII Domain Containing

Functions: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction

The "MFGE8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MFGE8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MFHAS1 | MFN1 | MFN2 | MFNG | MFRP | MFSD1 | MFSD10 | MFSD11 | MFSD12 | MFSD13A | MFSD14A | MFSD14B | MFSD14CP | MFSD2A | MFSD2B | MFSD3 | MFSD4A | MFSD4A-AS1 | MFSD4B | MFSD4B-DT | MFSD5 | MFSD6 | MFSD6L | MFSD8 | MFSD9 | MGA | MGAM | MGAM2 | MGARP | MGAT1 | MGAT2 | MGAT3 | MGAT3-AS1 | MGAT4A | MGAT4B | MGAT4C | MGAT4D | MGAT4EP | MGAT4FP | MGAT5 | MGAT5B | MGC12916 | MGC15885 | MGC16025 | MGC16275 | MGC27382 | MGC2889 | MGC32805 | MGC34796 | MGC4859 | MGC70870 | MGLL | MGME1 | MGMT | MGP | MGRN1 | MGST1 | MGST2 | MGST3 | MHRT | MIA | MIA-RAB4B | MIA2 | MIA3 | MIAT | MIATNB | MIB1 | MIB2 | MICA | MICA-AS1 | MICAL1 | MICAL2 | MICAL3 | MICALCL | MICALL1 | MICALL2 | MICB | MICB-DT | MICC | MICD | MICOS10 | MICOS10-NBL1 | MICOS10P1 | MICOS13 | Microfilament-associated triple complex | MicroRNA 1273d | MicroRNA 1273f | MicroRNA 1273g | MicroRNA 3607 | MicroRNA 3653 | MicroRNA 3656 | MicroRNA 4417 | MicroRNA 4419a | MicroRNA 4459 | MicroRNA 4461 | MicroRNA 4532 | MicroRNA 4792 | MicroRNA 5095 | MicroRNA 5096 | MicroRNA 6087