METTL5: A Potential Drug Target and Biomarker (G29081)

Target Name: METTL5

NCBI ID: G29081

METTL5

METTL5: A Potential Drug Target and Biomarker

METTL5 (RNA-protein interactions and methylation-modified N6-ad茅nylate-metyltransferase 5) is a gene that encodes a protein involved in the regulation of RNA metabolism. Specifically, METTL5 is an enzyme that adds a methyl group to the N6 position of adenosine in RNA, which is a critical step in the process of RNA degradation and is involved in various cellular processes, including translation, decay, and mRNA translation.

METTL5 has been identified as a potential drug target and biomarker due to its involvement in various cellular processes and its potential impact on disease. METTL5 has been shown to play a role in the regulation of cell proliferation, apoptosis, and translation, and is involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the key features of METTL5 is its role in the regulation of RNA metabolism, which is critical for the production and degradation of RNA molecules. METTL5 is involved in the addition of a methyl group to the N6 position of adenosine in RNA, which is a critical step in the process of RNA degradation. This process is important for the stability and translation of RNA molecules, and is involved in the regulation of various cellular processes, including translation, decay, and mRNA translation.

METTL5 is also involved in the regulation of cell proliferation and apoptosis. Research has shown that METTL5 has been shown to play a role in the regulation of cell cycle progression and the execution of apoptosis. METTL5 has been shown to promote the G1/S transition and the G2/M transition, which are critical steps in the regulation of cell proliferation. In addition, METTL5 has been shown to be involved in the regulation of apoptosis, as it has been shown to promote the execution of apoptotic programs in various cellular contexts.

METTL5 has also been shown to play a role in the regulation of translation and mRNA stability. METTL5 is involved in the addition of a methyl group to the N6 position of adenosine in RNA, which is a critical step in the process of RNA degradation. This process is important for the stability and translation of RNA molecules, and is involved in the regulation of various cellular processes, including translation, decay, and mRNA translation.

In addition to its role in the regulation of RNA metabolism, METTL5 has also been shown to play a role in the regulation of cellular processes that are critical for the development and progression of various diseases. For example, METTL5 has been shown to play a role in the regulation of cancer cell growth and the development of cancer. In addition, METTL5 has been shown to play a role in the regulation of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

METTL5 is also a potential biomarker for various diseases. For example, METTL5 has been shown to be involved in the regulation of translation and mRNA stability, which are critical steps in the development and progression of various diseases. In addition, METTL5 has been shown to play a role in the regulation of cell cycle progression and the execution of apoptosis, which are involved in the development and progression of neurodegenerative diseases.

In conclusion, METTL5 is a gene that encodes a protein involved in the regulation of RNA metabolism, and has been shown to play a role in the regulation of various cellular processes that are critical for the development and progression of various diseases. As a potential drug target and biomarker, METTL5 is a promising target for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of METTL5 in

Protein Name: Methyltransferase 5, N6-adenosine

Functions: Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (PubMed:31328227, PubMed:32217665, PubMed:33357433, PubMed:33428944, PubMed:35033535). N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation (PubMed:33357433)

The "METTL5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about METTL5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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