ACSBG1: A Protein of Interest for Alzheimer's Disease (G23205)

Target Name: ACSBG1

NCBI ID: G23205

ACSBG1

ACSBG1: A Protein of Interest for Alzheimer's Disease

ACSBG1, also known as bubblegum, is a protein that is expressed in the brain and has been shown to play a role in various neurological conditions, including Alzheimer's disease. The protein is made up of 230 amino acids and has a calculated molecular weight of 24.1 kDa. It is localized to the endoplasmic reticulum and is considered as a protein of interest in the field of neurodegenerative diseases.

One of the unique features of ACSBG1 is its ability to form aggregates in the brain, which is thought to play a role in the development and progression of neurodegenerative diseases. The aggregates of ACSBG1 have been shown to be toxic to nerve cells and to cause damage to the brain, which may contribute to the neurotoxicity associated with these diseases.

Additionally, ACSBG1 has been shown to interact with various other proteins, including tau, a protein that is known to be involved in the development of Alzheimer's disease. The interaction between ACSBG1 and tau has been shown to enhance the neurotoxicity of ACSBG1, suggesting that it may be a potential drug target or biomarker for Alzheimer's disease.

Another promising aspect of ACSBG1 is its potential to be used as a therapeutic agent. Researchers have been shown to be able to deliver small amounts of ACSBG1 into the brain and to achieve a significant increase in the amount of ACSBG1 available in the brain. This suggests that ACSBG1 could be an effective agent for treating neurodegenerative diseases, including Alzheimer's disease.

It is worth mentioning that there are several studies that are investigating the role of ACSBG1 in neurodegenerative diseases, and more research is needed to fully understand its function and potential as a drug target or biomarker.

In conclusion, ACSBG1 is a protein that has been shown to play a role in various neurological conditions, including Alzheimer's disease. Its ability to form aggregates in the brain and to interact with other proteins, including tau, makes it an attractive target for drug development. Further research is needed to fully understand its function and potential as a drug or biomarker.

Protein Name: Acyl-CoA Synthetase Bubblegum Family Member 1

Functions: Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:12975357, PubMed:24269233, PubMed:10954726). Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (PubMed:10954726)

The "ACSBG1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACSBG1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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