Target Name: HEY2
NCBI ID: G23493
Review Report on HEY2 Target / Biomarker Content of Review Report on HEY2 Target / Biomarker
HEY2
Other Name(s): cardiovascular basic helix-loop-helix factor 1 | class B basic helix-loop-helix protein 32 | hHRT2 | protein gridlock homolog | HESR2 | Hairy/enhancer-of-split related with YRPW motif protein 2 | HES-related repressor protein 1 | HERP | hCHF1 | HRT-2 | Hairy-related transcription factor 2 | hes related family bHLH transcription factor with YRPW motif 2 | CHF1 | HERP1 | HES-related repressor protein 2 | GRL | HEY2_HUMAN | cardiovascular helix-loop-helix factor 1 | HRT2 | Cardiovascular helix-loop-helix factor 1 | Protein gridlock homolog | Hairy and enhancer of split-related protein 2 | MGC10720 | OTTHUMP00000017138 | GRIDLOCK | bHLHb32 | Hes related family bHLH transcription factor with YRPW motif 2 | HESR-2 | hairy-related transcription factor 2 | Cardiovascular basic helix-loop-helix factor 1 | hairy/enhancer-of-split related with YRPW motif 2 | hairy and enhancer of split-related protein 2 | Class B basic helix-loop-helix protein 32

HEY2: A Protein Regulator of Cardiovascular and Tissue Function

The cardiovascular system is a vital organ that plays a crucial role in maintaining the overall health and wellbeing of a person. It is responsible for delivering oxygen and nutrients to all parts of the body and is also responsible for removing waste products from the blood. heart is the central organ of the cardiovascular system that pumps blood throughout the body. It is surrounded by various components that work together to ensure proper function. One of these components is the basic helix-loop-helix (BHLH) factor 1, also known as HEY2.

HEY2 is a protein that is found in the heart muscle cells. It is a key regulator of the heart's electrical activity, which is essential for proper heart function. The BHLH factor 1 gene is responsible for producing this protein. When a person has a genetic mutation that affects the production of BHLH factor 1, they may develop a condition known as hypokalemia. Hypokalemia is a condition in which the levels of potassium in the body are too low. This can have serious consequences, including muscle weakness, paralysis, and even cardiac arrhythmias.

HEY2 has also been shown to play a key role in the regulation of cell signaling pathways that control various cellular processes in the body. These signaling pathways are critical for the growth, development, and function of tissues and organs. The BHLH factor 1 gene is responsible for producing the HEY2 protein, which is then involved in regulating the activity of various signaling pathways.

HEY2 has also been shown to be involved in the regulation of ion channels in the heart. These channels are responsible for allowing and blocking the flow of electrical signals through the heart muscle cells. The BHLH factor 1 gene is responsible for producing the HEY2 protein, which is then involved in regulating the activity of the ion channels in the heart.

In addition to its role in regulating the heart's electrical activity, HEY2 has also been shown to be involved in the regulation of the heart's mechanical function. The heart muscle is responsible for pumping blood throughout the body, and its mechanical function is regulated by various factors , including the BHLH factor 1 gene. The HEY2 protein is involved in regulating the activity of the heart muscle cells, which is critical for maintaining proper heart function.

HEY2 has also been shown to play a key role in the regulation of cellular processes that are important for the development and function of tissues and organs. These processes include cell growth, cell division, and cell migration. The BHLH factor 1 gene is responsible for producing the HEY2 protein, which is then involved in regulating the activity of various signaling pathways that control these cellular processes.

In conclusion, HEY2 is a protein that plays a critical role in the regulation of various cellular processes that are important for the development and function of tissues and organs. It is also involved in the regulation of the heart's electrical activity, mechanical function, and ion channels. Given its involvement in these critical processes, HEY2 is a potential drug target or biomarker for a variety of cardiovascular and other conditions. Further research is needed to fully understand the role of HEY2 in the cardiovascular system and to develop effective treatments for conditions that are caused by defects in this protein.

Protein Name: Hes Related Family BHLH Transcription Factor With YRPW Motif 2

Functions: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6

The "HEY2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HEY2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HEY2-AS1 | HEYL | HFE | HFM1 | HGC6.3 | HGD | HGF | HGFAC | HGH1 | HGS | HGSNAT | HHAT | HHATL | HHEX | HHIP | HHIP-AS1 | HHIPL1 | HHIPL2 | HHLA1 | HHLA2 | HHLA3 | HIBADH | HIBCH | HIC1 | HIC2 | HID1 | HID1-AS1 | HIF1A | HIF1A-AS1 | HIF1A-AS2 | HIF1A-AS3 | HIF1AN | HIF3A | HIGD1A | HIGD1AP1 | HIGD1AP10 | HIGD1B | HIGD1C | HIGD2A | HIGD2B | High affinity cAMP-specif | High Affinity Immunoglobulin Epsilon Fc Receptor | HIKESHI | HILPDA | HILPDA-AS1 | HINFP | HINT1 | HINT1P1 | HINT2 | HINT3 | HIP1 | HIP1R | HIPK1 | HIPK1-AS1 | HIPK2 | HIPK3 | HIPK4 | HIRA | HIRIP3 | HISLA | Histamine Receptor (HR) | Histocompatibility antigen-related | Histone | Histone acetyltransferase (HAT) | Histone deacetylase | Histone H2A | Histone H2B | Histone H3 | Histone Lysine Demethylase | Histone methyltransferase | HIVEP1 | HIVEP2 | HIVEP3 | HJURP | HJV | HK1 | HK2 | HK2P1 | HK3 | HKDC1 | HLA Class II Histocompatibility Antigen DM (HLA-DM) | HLA class II histocompatibility Antigen DO (HLA-DO) | HLA class II histocompatibility antigen DP (HLA-DP) | HLA Class II Histocompatibility Antigen DQ8 | HLA class II histocompatibility antigen DR (HLA-DR) | HLA Class II Histocompatibility Antigen, DQ (HLA-DQ) | HLA class II histocompatibility antigen, DRB1-7 beta chain, transcript variant X1 | HLA complex group 16 (non-protein coding), transcript variant X2 | HLA complex group 8 | HLA-A | HLA-B | HLA-C | HLA-DMA | HLA-DMB | HLA-DOA | HLA-DOB | HLA-DPA1 | HLA-DPA2 | HLA-DPA3 | HLA-DPB1