Target Name: HEYL
NCBI ID: G26508
Review Report on HEYL Target / Biomarker Content of Review Report on HEYL Target / Biomarker
HEYL
Other Name(s): bHLHb33 | hes related family bHLH transcription factor with YRPW motif like | hHeyL | MGC12623 | Hairy/enhancer-of-split related with YRPW motif-like protein | HRT-3 | Hes related family bHLH transcription factor with YRPW motif like | HEYL_HUMAN | HEY3 | Class B basic helix-loop-helix protein 33 | class B basic helix-loop-helix protein 33 | HEY-like protein | Hairy-related transcription factor 3 | HESR3 | hairy-related transcription factor 3 | hHRT3 | HRT3 | hairy/enhancer-of-split related with YRPW motif 3

HEYL: A Protein Implicated in Multiple Diseases

HEYL (bHLHb33) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and pancreas. It is a member of the Hedgehog gene family, which is known for the involvement of this family of proteins in development and tissue repair.

HEYL has been shown to play a role in several important biological processes in the body, including cell proliferation, migration, and survival. It is also involved in the development and progression of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Due to its involvement in so many important processes in the body, HEYL has been identified as a potential drug target or biomarker. Researchers are currently exploring the use of drugs that can specifically target HEYL to treat a variety of different diseases.

One of the main advantages of targeting HEYL is its involvement in several key pathways that are involved in the development and progression of many diseases. This means that targeting HEYL with drugs can potentially have a broad impact on a variety of different conditions.

For example, HEYL has been shown to be involved in the development and progression of cancer. In fact, studies have shown that inhibiting HEYL can lead to a regression of cancer tumors in both cell cultures and animal models. This suggests that targeting HEYL may be an effective way to treat cancer.

HEYL is also involved in the development and progression of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. These conditions are characterized by the progressive loss of brain cells and can lead to a range of symptoms, including cognitive decline and difficulty with daily activities.

In addition to its involvement in neurodegenerative diseases, HEYL is also involved in the development and progression of autoimmune disorders. These conditions involve an immune system that becomes too active and leads to inflammation and damage in the body.

Targeting HEYL with drugs may also have the potential to treat other diseases, including heart disease and liver disease. These conditions are characterized by the buildup of plaque in the arteries or the buildup of fat in the liver, and can lead to serious health problems if left untreated.

In conclusion, HEYL is a protein that is involved in several important biological processes in the body. It has been shown to play a role in the development and progression of cancer, neurodegenerative diseases, and autoimmune disorders. As a result, targeting HEYL with drugs may have the potential to treat a wide range of different conditions. Further research is needed to fully understand the role of HEYL in these processes and to develop effective treatments.

Protein Name: Hes Related Family BHLH Transcription Factor With YRPW Motif Like

Functions: Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6

The "HEYL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HEYL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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