Target Name: HHEX
NCBI ID: G3087
Review Report on HHEX Target / Biomarker Content of Review Report on HHEX Target / Biomarker
HHEX
Other Name(s): Homeobox, hematopoietically expressed | homeobox protein PRH | Homeobox protein HEX | homeobox, hematopoietically expressed | HOX11L-PEN | hematopoietically expressed homeobox | proline-rich homeodomain-containing transcription factor | PRHX | HEX | Hematopoietically expressed homeobox | Proline-rich homeodomain-containing transcription factor | HMPH | PRH | HHEX_HUMAN | homeobox protein HEX | Homeobox protein PRH | Hematopoietically-expressed homeobox protein HHEX

HHEX: A Drug Target / Disease Biomarker

Human hexokinase (HHX) is a protein that is expressed in various tissues throughout the body, including the liver, heart, and kidneys. It is a key enzyme in the metabolism of hexokinones, a type of sugar that is found in many foods, such as fruits, vegetables, and whole grains. HHX is also involved in the breakdown of other types of sugar, such as glucose and fructose.

HHX is a protein that is expressed in the liver, heart, and kidneys, and it is involved in the metabolism of a type of sugar called hexokinone. This sugar is found in many foods, including fruits, vegetables, and whole grains. It is also involved in the breakdown of other types of sugar, such as glucose and fructose.

One of the things that makes HHX an interesting potential drug target is its role in the metabolism of hexokinones. This sugar is often used as a research agent to study how the body handles the intake of these types of sugars. Additionally, HHX is also involved in the breakdown of other types of sugar, which makes it a potential target for drugs that are used to treat conditions related to the metabolism of sugar, such as type 2 diabetes.

HHX is also a protein that is expressed in various tissues throughout the body, including the liver, heart, and kidneys. This makes it a potential target for drugs that are used to treat liver, heart, and kidney diseases.

In addition to its role in the metabolism of hexokinones and other types of sugar, HHX is also involved in the regulation of a variety of cellular processes. This makes it a potential target for drugs that are used to interfere with these processes, such as cancer, aging, and neurodegenerative diseases.

Overall, HHX is a protein that is involved in a variety of cellular processes that are important for the health and function of the body. As a result, it is an attractive target for drugs that are used to interfere with these processes. Further research is needed to fully understand the role of HHX in the body and its potential as a drug target.

Protein Name: Hematopoietically Expressed Homeobox

Functions: Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). May play a role in hematopoietic differentiation (PubMed:8096636)

The "HHEX Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HHEX comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HHIP | HHIP-AS1 | HHIPL1 | HHIPL2 | HHLA1 | HHLA2 | HHLA3 | HIBADH | HIBCH | HIC1 | HIC2 | HID1 | HID1-AS1 | HIF1A | HIF1A-AS1 | HIF1A-AS2 | HIF1A-AS3 | HIF1AN | HIF3A | HIGD1A | HIGD1AP1 | HIGD1AP10 | HIGD1B | HIGD1C | HIGD2A | HIGD2B | High affinity cAMP-specif | High Affinity Immunoglobulin Epsilon Fc Receptor | HIKESHI | HILPDA | HILPDA-AS1 | HINFP | HINT1 | HINT1P1 | HINT2 | HINT3 | HIP1 | HIP1R | HIPK1 | HIPK1-AS1 | HIPK2 | HIPK3 | HIPK4 | HIRA | HIRIP3 | HISLA | Histamine Receptor (HR) | Histocompatibility antigen-related | Histone | Histone acetyltransferase (HAT) | Histone deacetylase | Histone H2A | Histone H2B | Histone H3 | Histone Lysine Demethylase | Histone methyltransferase | HIVEP1 | HIVEP2 | HIVEP3 | HJURP | HJV | HK1 | HK2 | HK2P1 | HK3 | HKDC1 | HLA Class II Histocompatibility Antigen DM (HLA-DM) | HLA class II histocompatibility Antigen DO (HLA-DO) | HLA class II histocompatibility antigen DP (HLA-DP) | HLA Class II Histocompatibility Antigen DQ8 | HLA class II histocompatibility antigen DR (HLA-DR) | HLA Class II Histocompatibility Antigen, DQ (HLA-DQ) | HLA class II histocompatibility antigen, DRB1-7 beta chain, transcript variant X1 | HLA complex group 16 (non-protein coding), transcript variant X2 | HLA complex group 8 | HLA-A | HLA-B | HLA-C | HLA-DMA | HLA-DMB | HLA-DOA | HLA-DOB | HLA-DPA1 | HLA-DPA2 | HLA-DPA3 | HLA-DPB1 | HLA-DPB2 | HLA-DQA1 | HLA-DQA2 | HLA-DQB1 | HLA-DQB1-AS1 | HLA-DQB2 | HLA-DRA | HLA-DRB1 | HLA-DRB2 | HLA-DRB3 | HLA-DRB4 | HLA-DRB5 | HLA-DRB6 | HLA-DRB7