FUT10: A Key Player in Fucose Metabolism and Disease (G84750)

FUT10: A Key Player in Fucose Metabolism and Disease

FUT10, also known as Galactoside 3-L-fucosyltransferase 10, is a gene that has been identified as a potential drug target or biomarker for a variety of diseases. The FUT10 gene is a key player in the metabolism of fucose, a type of sugar found in many foods, including fruits, vegetables, and dairy products.

FUT10 is a enzyme that catalyzes the transfer of a fucose molecule to a specific protein, known as GLUT1. This transfer reaction is a critical step in the metabolism of fucose, and is involved in the production of many important biological molecules, including cellulose, chitin, and other complex carbohydrates.

Studies have suggested that disruptions in the FUT10 gene have been linked to a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders. In addition, evidence has also suggested that FUT10 may play a role in the regulation of immune responses and inflammation.

One potential approach to targeting FUT10 as a drug or biomarker is to develop small molecules that can modulate the activity of the FUT10 enzyme. This could involve a range of strategies, including the use of chemical inhibitors,RNA interference, or genetic modifiers to alter the activity of FUT10.

Another approach to studying FUT10 as a potential drug or biomarker is to investigate the effects of drugs on the expression and activity of FUT10. This could involve a range of techniques, including RNA sequencing, qRT-PCR, and mass spectrometry to measure changes in gene expression and protein levels in response to drug treatment.

In addition to these approaches, there is also potential to use FUT10 as a biomarker to diagnose or monitor the progression of certain diseases. For example, by measuring the level of FUT10 activity in cancer cells or in samples from individuals with neurodegenerative diseases, researchers could potentially use FUT10 as a diagnostic or monitoring tool.

Overall, the FUT10 gene is a promising target for drug development and research into the biology of fucose metabolism and its role in disease. Further studies are needed to fully understand the potential of FUT10 as a drug or biomarker, and to develop effective strategies for targeting this protein in order to improve human health.

Protein Name: Fucosyltransferase 10

Functions: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation (PubMed:19088067). Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (By similarity)

The "FUT10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FUT10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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FUT11 | FUT2 | FUT3 | FUT4 | FUT5 | FUT6 | FUT7 | FUT8 | FUT8-AS1 | FUT9 | FUZ | FXN | FXR1 | FXR2 | FXYD1 | FXYD2 | FXYD3 | FXYD4 | FXYD5 | FXYD6 | FXYD6-FXYD2 | FXYD7 | FYB1 | FYB2 | FYCO1 | FYN | FYTTD1 | FZD1 | FZD10 | FZD10-AS1 | FZD2 | FZD3 | FZD4 | FZD4-DT | FZD5 | FZD6 | FZD7 | FZD8 | FZD9 | FZR1 | G protein-Coupled Inwardly-Rectifying Potassium Channel (GIRK) | G Protein-Coupled Receptor Kinases (GRKs) | G0S2 | G2E3 | G2E3-AS1 | G3BP1 | G3BP2 | G6PC1 | G6PC2 | G6PC3 | G6PD | GA-binding protein | GAA | GAB1 | GAB2 | GAB3 | GAB4 | GABA(A) receptor | GABARAP | GABARAPL1 | GABARAPL2 | GABARAPL3 | GABBR1 | GABBR2 | GABPA | GABPAP | GABPB1 | GABPB1-AS1 | GABPB1-IT1 | GABPB2 | GABRA1 | GABRA2 | GABRA3 | GABRA4 | GABRA5 | GABRA6 | GABRB1 | GABRB2 | GABRB3 | GABRD | GABRE | GABRG1 | GABRG2 | GABRG3 | GABRG3-AS1 | GABRP | GABRQ | GABRR1 | GABRR2 | GABRR3 | GACAT1 | GACAT2 | GACAT3 | GAD1 | GAD2 | GADD45A | GADD45B | GADD45G | GADD45GIP1 | GADL1