FUT6: Key Regulator of Cell Division and Disease (G2528)

Target Name: FUT6

NCBI ID: G2528

FUT6

FUT6: Key Regulator of Cell Division and Disease

FUT6 (F6U-TIMP2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of the timing of cell division and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the unique features of FUT6 is its ability to interact with the protein TIMP2, which is also known as branch protein 2. This interaction allows FUT6 to regulate the activity of other proteins, including those involved in cell division, metabolism, and inflammation.

FUT6 is also known as FT1A, which stands for FUT6-TIMP2. This name is derived from the names of the proteins it interacts with, FUT6 and TIMP2.

FUT6 is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, and kidneys. It is a key regulator of the timing of cell division and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the unique features of FUT6 is its ability to interact with the protein TIMP2, which is also known as branch protein 2. This interaction allows FUT6 to regulate the activity of other proteins, including those involved in cell division, metabolism, and inflammation.

FUT6 is also known as FT1A, which stands for FUT6-TIMP2. This name is derived from the names of the proteins it interacts with, FUT6 and TIMP2.

The FUT6 gene is located on chromosome 6 and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders. It is thought to play a role in regulating the timing of cell division and in the development of these diseases.

Studies have shown that FUT6 is involved in a number of important biological processes, including cell division, DNA replication, and repair, as well as metabolism and inflammation. It is also involved in the regulation of cell survival and in the development of a variety of diseases.

One of the most promising aspects of FUT6 is its potential as a drug target or biomarker. Studies have shown that FUT6 is involved in a number of diseases and that inhibiting its activity may be a useful way to treat these diseases.

In addition to its potential as a drug target, FUT6 is also a potential biomarker for a variety of diseases. Its expression is often reduced in tissues or cells affected by cancer, neurodegenerative diseases, and other disorders, and its levels may be used as a diagnostic or monitoring tool.

Overall, FUT6 is a protein that is important for understanding the biology of cell division and the development of various diseases. Further research is needed to fully understand its role and its potential as a drug target or biomarker.

Protein Name: Fucosyltransferase 6

Functions: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein- or a glycolipid-linked sialopolylactosamines chain or of a distal or internal lactosamine unit of a neutral glycoprotein- or a glycolipid-linked polylactosamines chain through an alpha-1,3 glycosidic linkage and participates in surface expression of the sialyl Lewis X (sLe(x)), Lewis X (Le(x)) and non sialylated VIM2 determinants (PubMed:9451035, PubMed:1520296, PubMed:1339443, PubMed:7650030, PubMed:17604274, PubMed:9363434, PubMed:10728707, PubMed:29593094). Moreover transfers fucose to H-type 2 (Fucalpha1-2Galbeta1-4GlcNAc) chain acceptor substrates and participates in difucosylated sialyl Lewis x determinants (PubMed:17604274, PubMed:1339443). Also fucosylates a polylactosamine substrate having a 6 sulfate modification at the GlcNAc moiety and gives rise to sialyl and non-sialyl 6-sulfo lewis X (PubMed:10728707). Does not have activity towards type 1 ((Galbeta1-3GlcNAc)) and H-type 1 chain (Fucalpha1-2Galbeta1-3GlcNAc) acceptors substrates (PubMed:1339443, PubMed:17604274, PubMed:9363434)

The "FUT6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FUT6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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