FUNDC2P2: A Potential Drug Target for Various Diseases (G388965)
FUNDC2P2: A Potential Drug Target for Various Diseases
FUNDC2P2, also known as FUN14, is a gene located on chromosome 16 that has been identified as a potential drug target or biomarker for various diseases. The gene is composed of two pseudogenes, Fun13 and Fun14, which encode for a protein with unknown function. The Fun13 gene has been shown to be involved in cell adhesion, while the Fun14 gene has been shown to be involved in the regulation of cell survival.
Targeting
One of the main targets of FUNDC2P2 is the regulation of cell death. According to the literature, the protein encoded by the Fun14 gene has been found to play important roles in a variety of diseases, including neurodegenerative diseases, cardiovascular diseases, and cancer. Studies have found that the protein encoded by the Fun14 gene can inhibit apoptosis and may become a target for anti-tumor drugs.
Another target is its functions related to cell migration and angiogenesis. Studies have shown that the protein encoded by the Fun13 gene plays an important role in tumor growth and angiogenesis. Therefore, the researchers believe that the Fun13 gene may be a potential drug target for the treatment of various tumors.
biology
The FUNDC2P2 gene is located on chromosome 16 and is a coding region that includes two exons. The Fun13 gene exon includes 199 amino acids, while the Fun14 gene exon includes 144 amino acids. Both exons contain multiple conserved amino acids, such as glutamic acid, asparagine, and glutamine. These conserved amino acids have important biological functions in cells and may play an important role in protein function.
Pharmacology
During the drug screening process, researchers found that multiple drugs interact with the protein encoded by the FunDC2P2 gene. These drugs include antineoplastic drugs, anti-inflammatory drugs, and neuroprotective drugs. These drugs may interact with the FunDC2P2 gene in a variety of ways, thereby affecting its function.
Clinical application
Currently, the protein encoded by the FunDC2P2 gene has not been widely used in clinical treatments. However, with the continuous development of science and technology, researchers believe that it may be used as a new drug target to treat a variety of diseases in the future. For example, by inhibiting the protein encoded by the FunDC2P2 gene, diseases such as neurodegenerative diseases, cardiovascular diseases, and tumors can be treated.
Conclusion
The FUNDC2P2 gene is a coding region that includes two exons, namely Fun13 and Fun14. These exons contain multiple conserved amino acids that may play an important role in protein function. During the drug screening process, researchers found that multiple drugs interact with the protein encoded by the FunDC2P2 gene. Although it has not yet been applied to clinical treatment, with the continuous development of science and technology, it may be used as a new drug target to treat a variety of diseases in the future.
Protein Name: FUN14 Domain Containing 2 Pseudogene 2
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More Common Targets
FUNDC2P3 | FUOM | FURIN | FUS | FUT1 | FUT10 | FUT11 | FUT2 | FUT3 | FUT4 | FUT5 | FUT6 | FUT7 | FUT8 | FUT8-AS1 | FUT9 | FUZ | FXN | FXR1 | FXR2 | FXYD1 | FXYD2 | FXYD3 | FXYD4 | FXYD5 | FXYD6 | FXYD6-FXYD2 | FXYD7 | FYB1 | FYB2 | FYCO1 | FYN | FYTTD1 | FZD1 | FZD10 | FZD10-AS1 | FZD2 | FZD3 | FZD4 | FZD4-DT | FZD5 | FZD6 | FZD7 | FZD8 | FZD9 | FZR1 | G protein-Coupled Inwardly-Rectifying Potassium Channel (GIRK) | G Protein-Coupled Receptor Kinases (GRKs) | G0S2 | G2E3 | G2E3-AS1 | G3BP1 | G3BP2 | G6PC1 | G6PC2 | G6PC3 | G6PD | GA-binding protein | GAA | GAB1 | GAB2 | GAB3 | GAB4 | GABA(A) receptor | GABARAP | GABARAPL1 | GABARAPL2 | GABARAPL3 | GABBR1 | GABBR2 | GABPA | GABPAP | GABPB1 | GABPB1-AS1 | GABPB1-IT1 | GABPB2 | GABRA1 | GABRA2 | GABRA3 | GABRA4 | GABRA5 | GABRA6 | GABRB1 | GABRB2 | GABRB3 | GABRD | GABRE | GABRG1 | GABRG2 | GABRG3 | GABRG3-AS1 | GABRP | GABRQ | GABRR1 | GABRR2 | GABRR3 | GACAT1 | GACAT2 | GACAT3 | GAD1
