IFI6: A Potential Drug Target and Biomarker (G2537)

Target Name: IFI6

NCBI ID: G2537

IFI6

IFI6: A Potential Drug Target and Biomarker

IFI6 (Immunofluorescence Injection Protocol 6) is a technique used for the detection and analysis of proteins in various biological samples such as tissues, cells, and body fluids. It is a widely used method in many fields, including biology, medicine, and agriculture. In recent years, IFI6 has gained significant attention as a potential drug target and biomarker due to its ability to label proteins with high sensitivity and specificity.

The protein G1P3, also known as IFI6, is a key regulator of the actinin-associated protein (AAP) complex, which is involved in a wide range of cellular processes such as cell adhesion, migration, and invasion. The G1P3 protein plays a crucial role in the regulation of actinin dynamics and in the formation of the AAP complex, which is composed of the protein AAP and the nucleotide GDP.

The G1P3 protein is a 21-kDa protein that consists of 120 amino acid residues. It has a distinct N-terminal and C-terminal region, with a N-terminal region that contains a putative N-endopeptide loop and a C-terminal region that contains a putative C-endopeptide loop. The G1P3 protein is highly conserved across various species, with only minor differences in its amino acid sequence.

One of the key functions of the G1P3 protein is its role in the regulation of actinin dynamics. Actinins are a type of protein that can interact with actinin monomers and form a stable complex. The G1P3 protein plays a crucial role in the regulation of actinin monomer formation, stability, and dissociation from the actinin monomer.

The G1P3 protein is involved in the formation of the AAP complex, which is composed of the protein AAP and the nucleotide GDP. The AAP protein is a key regulator of actinin dynamics and is involved in a wide range of cellular processes, including cell adhesion, migration, and invasion. The G1P3 protein plays a crucial role in the regulation of AAP stability and stability of the AAP-GDP complex.

In addition to its role in actinin regulation, the G1P3 protein is also involved in the regulation of many other cellular processes. For example, the G1P3 protein is involved in the regulation of cell cycle progression, apoptosis, and cell signaling. It is also involved in the regulation of cytokine signaling, inflammation, and stress responses.

The G1P3 protein is a potential drug target due to its involvement in a wide range of cellular processes. Its high conservation across various species and its role in actinin regulation make it an attractive target for drug development. Additionally, the G1P3 protein is also a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In conclusion, the G1P3 protein is a key regulator of actinin dynamics and plays a crucial role in the regulation of many cellular processes. Its high conservation and involvement in actinin regulation make it an attractive target for drug development and a potential biomarker for various diseases. Further research is needed to fully understand the role of the G1P3 protein in cellular processes and its potential as a drug target and biomarker.

Protein Name: Interferon Alpha Inducible Protein 6

Functions: Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (PubMed:15685448, PubMed:17823654, PubMed:26244642). However, it has also been shown to have a pro-apoptotic activity (PubMed:27673746). Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571)

The "IFI6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IFI6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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