Target Name: WHRN
NCBI ID: G25861
Review Report on WHRN Target / Biomarker Content of Review Report on WHRN Target / Biomarker
WHRN
Other Name(s): Whirlin, transcript variant 3 | WHRN variant 2 | Whirlin (isoform 1) | USH2D | Whirlin, transcript variant 2 | Autosomal recessive deafness type 31 protein | autosomal recessive deafness type 31 protein | Whirlin | WHRN_HUMAN | Whirlin, transcript variant 1 | Whirlin (isoform 2) | CASK-interacting protein CIP98 | WHRN variant 1 | PDZD7B | Whirlin (isoform 3) | CIP98 | WHRN variant 3 | DFNB31 | whirlin | WI

WHRN: A Potential Drug Target Or Biomarker

WHRN (Whirlin, transcript variant 3) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell growth, differentiation, and survival, and is involved in a wide range of physiological processes. In recent years, researchers have become increasingly interested in WHRN as a potential drug target or biomarker, due to its unique structure and biology.

Structure and Localization

WHRN is a 21-kDa protein that is expressed in the brain, heart, and kidneys. It is composed of a unique transmembrane domain that is characterized by a conserved cytoplasmic region and a series of N-terminal transmembrane segments. The cytoplasmic region of WHRN contains a unique protein that is involved in the regulation of the actin cytoskeleton, while the N-terminal transmembrane segments contain a variety of domains that are involved in the regulation of cell growth, differentiation, and survival.

WHRN is primarily localized to the cytoplasm of various cell types, including neurons, astrocytes, and pericytes. It is also expressed in the endoplasmic reticulum (ER) and is thought to play a role in regulating the delivery of new proteins to the plasma membrane. In addition, WHRN is also expressed in the ribosome, which is responsible for the production of proteins, suggesting a role for WHRN in protein synthesis.

Function

WHRN is involved in a wide range of physiological processes that are important for the survival and growth of cells. It is a key regulator of cell growth and differentiation, as well as the regulation of cell survival and stress resistance. WHRN is also involved in the regulation of angiogenesis, the formation of new blood vessels, and in the regulation of the immune response.

One of the most significant functions of WHRN is its role in the regulation of cell growth and differentiation. WHRN plays a key role in the regulation of cell proliferation by promoting the growth of cells and by inhibiting the growth of cells that are no longer needed. This is accomplished through the regulation of several key signaling pathways, including the TGF-β pathway and the Wnt pathway.

In addition to its role in cell growth and differentiation, WHRN is also involved in the regulation of cell survival and stress resistance. It is a key regulator of apoptosis, which is the process by which cells are programmed to die, and is involved in the Regulation of cell death in response to a variety of stimuli, including stress and exposure to toxins.

WHRN is also involved in the regulation of angiogenesis, the formation of new blood vessels, and in the regulation of the immune response. It is a key regulator of the vascular endothelial growth factor (VEGF) signaling pathway, which is involved in the regulation of angiogenesis, and is also involved in the regulation of the immune response by promoting the production of immune cells and by regulating the activity of immune cells.

Drug Targeting

WHRN is a unique protein that has potential as a drug target or biomarker due to its unique structure and biology. Researchers have identified several potential drug targets for WHRN, including the TGF-β pathway, the Wnt pathway, the ER stress response, and the regulation of cell apoptosis.

The TGF-β pathway is a key signaling pathway that is involved in the regulation of cell growth and differentiation, and is thought to be involved in the regulation of WHRN. Researchers have identified several potential drug targets for the TGF-β pathway, including the Smad signaling pathway, which is involved in the regulation of cell growth and differentiation, and the FGF signaling pathway, which is involved in the regulation of cell growth and differentiation.

The Wnt pathway is a signaling pathway that is involved in the regulation of cell growth and development, and is also thought to be involved in the regulation of WHRN. Researchers have identified several potential drug targets for the Wnt pathway, including the FGF signaling pathway, which is involved in the regulation of cell growth and differentiation, and the

Protein Name: Whirlin

Functions: Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport

The "WHRN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WHRN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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