Target Name: RCHY1
NCBI ID: G25898
Review Report on RCHY1 Target / Biomarker Content of Review Report on RCHY1 Target / Biomarker
RCHY1
Other Name(s): Zinc finger protein 363 | PIRH2 | ZN363_HUMAN | Ring finger and CHY zinc finger domain containing 1, transcript variant 1 | ring finger and CHY zinc finger domain containing 1 | RING finger and CHY zinc finger domain-containing protein 1 (isoform 1) | CH-rich interacting match with PLAG1 | E3 ubiquitin-protein ligase Pirh2 | hARNIP | p53-induced RING-H2 protein | p53-induced protein with a RING-H2 domain | RING finger and CHY zinc finger domain-containing protein 1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | RING-type E3 ubiquitin transferase RCHY1 | RING finger protein 199 | CHIMP | androgen-receptor N-terminal-interacting protein | zinc finger protein 363 | Androgen receptor N-terminal-interacting protein | CH-rich-interacting match with PLAG1 | hPirh2 | RCHY1 variant 1 | zinc finger, CHY-type | ZCHY | ZNF363 | PRO1996 | RNF199 | ARNIP

Potential Drug Target for RCHY1 in Neurodegenerative Diseases

RCHY1, also known as Zinc finger protein 363, is a protein that is expressed in a variety of tissues throughout the body. It is a zinc finger gene that is characterized by the presence of a zinc finger domain in its protein sequence. The zinc finger domain is a structural protein that is composed of a series of amino acids that are modified with a zinc atom. This structural feature is unique and is associated with a variety of cellular processes, including DNA replication, gene regulation, and signaling pathways.

The RCHY1 gene has been identified as a potential drug target in the field of neurodegenerative diseases. Specifically, RCHY1 has been shown to be involved in the development and progression of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In addition , RCHY1 has also been shown to be involved in the development of other neurodegenerative diseases, including motor neuron disease and chronic pain.

Disease association

RCHY1 has been associated with a number of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and chronic pain. In addition, RCHY1 has also been shown to be involved in the development of other neurodegenerative diseases, including motor neuron disease and chronic pain. pain.

Parkinson's disease is a neurodegenerative disorder that is characterized by the loss of motor neurons in the brain. Studies have shown that RCHY1 is expressed in the brains of individuals with Parkinson's disease and that it is involved in the development and progression of the disease. In addition , studies have also shown that inhibiting RCHY1 can protect against the development and progression of Parkinson's disease.

Alzheimer's disease is a neurodegenerative disorder that is characterized by the accumulation of neurofibrillary tangles and senile plaques in the brain. Studies have shown that RCHY1 is expressed in the brains of individuals with Alzheimer's disease and that it is involved in the development and progression of the disease . In addition, studies have also shown that inhibiting RCHY1 can protect against the development and progression of Alzheimer's disease.

Huntington's disease is a neurodegenerative disorder that is characterized by the accumulation of huntingtin protein in the brain. Studies have shown that RCHY1 is expressed in the brains of individuals with Huntington's disease and that it is involved in the development and progression of the disease. In addition , studies have also shown that inhibiting RCHY1 can protect against the development and progression of Huntington's disease.

Chronic pain is a common complaint that is experienced by millions of people worldwide. Studies have shown that RCHY1 is involved in the development and progression of chronic pain and that it may play a role in the development of certain types of chronic pain.

Drug targeting

RCHY1 has been shown to be a potential drug target in the field of neurodegenerative diseases. Specifically, RCHY1 has been shown to be involved in the development and progression of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In addition, RCHY1 has also been shown to be involved in the development of other neurodegenerative diseases, including motor neuron disease and chronic pain.

Targeting RCHY1

Currently, there are several drugs that are being developed to target RCHY1 in the field of neurodegenerative diseases. These drugs are designed to inhibit the activity of RCHY1 and to reduce the production of RCHY1 in the brains of individuals with neurodegenerative diseases.

One of the drugs being developed to target RCHY1 is Concanavalin A (D SP-2001). Concanavalin A is a small molecule that is derived from a plant called Capsimax. Studies have shown that Concanavalin A is able to inhibit the activity of RCHY1 and to reduce the production of RCHY1 in the brains of individuals with neurodegenerative diseases. In addition, concanadin A has been shown to be safe and to have minimal side effects.

Another drug being developed to

Protein Name: Ring Finger And CHY Zinc Finger Domain Containing 1

Functions: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity

The "RCHY1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RCHY1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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