GDF11: A Protein with Potential Therapeutic Applications (G10220)

Target Name: GDF11

NCBI ID: G10220

GDF11

GDF11: A Protein with Potential Therapeutic Applications

GDF11 is a protein that is expressed in a variety of tissues throughout the body, including bone marrow, fat tissue, and the skin. It is a member of the GDF11 gene family, which is characterized by the presence of a specific genetic coding region that is responsible for the production of a protein with a critical role in cell signaling.

One of the unique features of GDF11 is its ability to stimulate the growth and differentiation of bone marrow cells. This is important because bones are critical for the support and structure of the body, and they are constantly being subjected to mechanical stress that can cause them to become fragile and susceptible to breaking. By stimulating the growth and differentiation of bone marrow cells, GDF11 may have the potential to repair damaged bones and help prevent the development of osteoporosis.

Another important function of GDF11 is its role in regulating inflammation. Inflammation is a natural response of the immune system, but when it becomes chronic or uncontrolled, it can cause a range of health problems, including chronic pain, autoimmune diseases, and even heart disease. GDF11 has been shown to have anti-inflammatory properties, which may make it a potential therapeutic target for a variety of conditions.

In addition to its potential therapeutic applications, GDF11 is also of interest as a drug target. The GDF11 gene has been shown to be involved in a number of cellular processes that are important for drug development, including cell signaling, cell adhesion, and cell migration. This makes it an attractive target for researchers who are looking for new treatments for a variety of conditions.

GDF11 is also of interest as a biomarker for a variety of diseases. Its ability to stimulate the growth and differentiation of bone marrow cells makes it a potential indicator of bone health. This may be useful for diagnosing conditions such as osteoporosis, where bones become fragile and are at risk of breaking. Similarly, GDF11's anti-inflammatory properties may make it a potential indicator of the effectiveness of certain treatments for inflammatory diseases.

In conclusion, GDF11 is a protein that is expressed in a variety of tissues throughout the body and has a range of potential therapeutic applications. Its ability to stimulate the growth and differentiation of bone marrow cells, as well as its anti-inflammatory properties, make it an attractive target for researchers who are looking for new treatments for a variety of conditions. Further research is needed to fully understand the role of GDF11 in cell signaling and its potential as a drug and biomarker.

Protein Name: Growth Differentiation Factor 11

Functions: Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues (By similarity). It is required for proper vertebral patterning and orofacial development (PubMed:31215115). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634)

The "GDF11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GDF11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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