GDF5: Key Regulator of Cellular Processes and Potential Drug Target

Target Name: GDF5

NCBI ID: G8200

GDF5

GDF5: Key Regulator of Cellular Processes and Potential Drug Target

GDF5 (Glycophosphate-dependent faithfulness factor) is a protein that is expressed in various tissues throughout the body. It is a key regulator of cellular processes such as cell adhesion, migration, and invasion, and is involved in the development and progression of many diseases. GDF5 has also been identified as a potential drug target and biomarker for several diseases.

GDF5 is a member of the family of the Faithful Protein (FP) family, which includes proteins that are involved in a variety of cellular processes. These proteins are characterized by a specific domain that includes a conserved catalytic core and a variable region that is involved in interactions with other proteins. The conserved catalytic core is responsible for the structural stability of the protein, while the variable region is involved in the recognition and interaction with other proteins.

GDF5 is a 21-kDa protein that is expressed in various tissues throughout the body. It is highly expressed in the brain, where it is involved in the development and progression of neurodegenerative diseases. GDF5 is also expressed in other tissues, including the heart, lungs, and gastrointestinal tract. It is highly expressed in the lungs, where it is involved in the regulation of cell adhesion and migration.

GDF5 is involved in many cellular processes that are critical for the development and progression of diseases. For example, it is involved in the regulation of cell adhesion, which is critical for the development of tissues and organs. GDF5 helps to maintain the structural stability of cells and allows them to stick together to form tissues. It is also involved in the regulation of cell migration, which is critical for the development and progression of diseases such as cancer. GDF5 helps to regulate the movement of cells, allowing them to move to new locations and participate in the development of tissues.

GDF5 is also involved in the regulation of many cellular processes that are important for the overall health of the body. For example, it is involved in the regulation of inflammation, which is critical for the immune system's response to infection. GDF5 helps to regulate the production of pro-inflammatory cytokines, which are important for the immune system's response to infection. It is also involved in the regulation of cell apoptosis, which is the process by which cells die when they are no longer needed. GDF5 helps to regulate the apoptosis of cells, which is important for the maintenance of tissue homeostasis and the development and progression of diseases.

GDF5 has also been identified as a potential drug target and biomarker for several diseases. For example, GDF5 has been identified as a potential drug target for neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. GDF5 has also been identified as a potential biomarker for these diseases, as its levels have been shown to be altered in the brains of individuals with neurodegenerative diseases. Additionally, GDF5 has been identified as a potential drug target for cancer, as it has been shown to be involved in the regulation of cell division and the development of tumors.

GDF5 is also involved in the regulation of many other cellular processes that are important for the overall health of the body. For example, it is involved in the regulation of cell growth, which is critical for the development and progression of tissues and organs. GDF5 helps to regulate the growth of cells, allowing them to grow and divide in a controlled manner. It is also involved in the regulation of cell differentiation, which is critical for the development and specification of tissues and organs. GDF5 helps to regulate the differentiation of cells, allowing them to develop into specific types of cells.

In conclusion, GDF5 is a protein that is involved in many cellular processes that are critical for the development and progression of diseases. It is highly expressed in the brain and other tissues, and is involved in the regulation of cell adhesion, migration, and many other cellular processes. GDF5 has also been identified as a potential drug target and biomarker for several diseases, including neurodegenerative diseases, cancer, and

Protein Name: Growth Differentiation Factor 5

Functions: Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (PubMed:24098149, PubMed:21976273, PubMed:15530414, PubMed:25092592). Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG (PubMed:21976273). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11276205)

The "GDF5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GDF5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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