Target Name: AMPD2
NCBI ID: G271
Review Report on AMPD2 Target / Biomarker Content of Review Report on AMPD2 Target / Biomarker
AMPD2
Other Name(s): OTTHUMP00000013369 | AMPD2 variant 5 | OTTHUMP00000233634 | Adenosine monophosphate deaminase 2, transcript variant 1 | adenosine monophosphate deaminase 2 (isoform L) | AMP deaminase 2 (isoform 4) | AMPD2 variant 1 | adenosine monophosphate deaminase 2 | OTTHUMP00000233629 | OTTHUMP00000233627 | PCH9 | OTTHUMP00000233630 | SPG63 | OTTHUMP00000013370 | Adenosine monophosphate deaminase 2, transcript variant 5 | OTTHUMP00000233633 | AMPD | AMP deaminase isoform L | AMPD2_HUMAN | Adenosine monophosphate deaminase 2 (isoform L) | AMP deaminase 2 | AMP deaminase 2 isoform 1

AMPD2: A Potential Drug Target and Biomarker for the Treatment of Ovarian Cancer

Ovarian cancer is a leading cause of cancer death in women, with a high incidence and a poor prognosis. Despite advances in the treatment of early-stage ovarian cancer, the majority of patients still experience relapse or recurrence, highlighting the need for new and more effective therapies. The identification of potential drug targets and biomarkers could provide new avenues for the development of more targeted and effective treatments. In this article, we will explore AMPD2, a potential drug target and biomarker for the treatment of ovarian cancer.

AMPD2: The Basics

AMPD2 (short for \"Accessible Motility Potential Driven Evolutionary Linguistics 2\"), is a protein that is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract. It is a member of the AMP-activated protein (AMP) family, which includes several other proteins that play important roles in cellular signaling and metabolism.

Recent studies have suggested that AMPD2 may have a role in the development and progression of ovarian cancer. Several studies have shown that high levels of AMPD2 are associated with poor prognosis in ovarian cancer patients, and that inhibition of AMPD2 has been shown to improve the efficacy of some chemotherapy drugs.

Potential Drug Target

The identification of a potential drug target is an important first step in the development of new treatments for ovarian cancer. By targeting AMPD2, researchers could potentially inhibit the growth and progression of ovarian cancer cells. This could be achieved through a variety of mechanisms, such as inhibiting the activity of AMPD2 itself, or by targeting cells that are dependent on AMPD2 for their growth and survival.

In addition to its potential as a drug target, AMPD2 has also been identified as a potential biomarker for ovarian cancer. The presence of high levels of AMPD2 in cancer cells can be used as a indicator of the disease, and could potentially be used as a diagnostic tool for ovarian cancer. This could be important for identifying early-stage disease and improving treatment outcomes.

Biomarker Potential

The identification of biomarkers for ovarian cancer is a critical step in the development of new treatments for the disease. Biomarkers can help researchers understand the underlying mechanisms of ovarian cancer, and can be used to monitor the effectiveness of different treatments.

Studies have shown that AMPD2 is expressed in various tissues and cell types, including cancer cells, nerve cells, and immune cells. This suggests that it may be a useful biomarker for ovarian cancer, particularly for identifying the primary source of the disease.

In addition to its potential as a biomarker, AMPD2 has also been shown to be involved in the development of ovarian cancer. Studies have shown that high levels of AMPD2 are associated with poor prognosis in ovarian cancer patients, and that inhibition of AMPD2 has been shown to improve the efficacy of some chemotherapy drugs. This suggests that AMPD2 may be a useful target for the treatment of ovarian cancer.

Conclusion

In conclusion, AMPD2 is a protein that has been identified as a potential drug target and biomarker for the treatment of ovarian cancer. Its high expression levels and association with poor prognosis in ovarian cancer patients make it an attractive target for the development of new and more effective therapies. Further research is needed to fully understand the role of AMPD2 in the development and progression of ovarian cancer, and to determine its potential as a biomarker for the disease.

Protein Name: Adenosine Monophosphate Deaminase 2

Functions: AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle

The "AMPD2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AMPD2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

AMPD3 | AMPH | AMT | AMTN | AMY1A | AMY1B | AMY1C | AMY2A | AMY2B | Amylin receptor | Amyloid beta A4 precursor protein-binding family (APP-BP) | AMZ1 | AMZ2 | AMZ2P1 | Anandamide membrane transporter (AMT) | ANAPC1 | ANAPC10 | ANAPC10P1 | ANAPC11 | ANAPC13 | ANAPC15 | ANAPC16 | ANAPC1P1 | ANAPC1P2 | ANAPC2 | ANAPC4 | ANAPC5 | ANAPC7 | ANG | ANGEL1 | ANGEL2 | Angiogenic Factor | Angiotensin receptor (AT) | ANGPT1 | ANGPT2 | ANGPT4 | ANGPTL1 | ANGPTL2 | ANGPTL3 | ANGPTL4 | ANGPTL5 | ANGPTL6 | ANGPTL7 | ANGPTL8 | ANHX | ANK1 | ANK2 | ANK3 | ANKAR | ANKDD1A | ANKDD1B | ANKEF1 | ANKFN1 | ANKFY1 | ANKH | ANKHD1 | ANKHD1-EIF4EBP3 | ANKIB1 | ANKK1 | ANKLE1 | ANKLE2 | ANKMY1 | ANKMY2 | ANKRA2 | ANKRD1 | ANKRD10 | ANKRD11 | ANKRD12 | ANKRD13A | ANKRD13B | ANKRD13C | ANKRD13D | ANKRD16 | ANKRD17 | ANKRD18A | ANKRD18B | ANKRD18CP | ANKRD18DP | ANKRD19P | ANKRD2 | ANKRD20A1 | ANKRD20A11P | ANKRD20A12P | ANKRD20A13P | ANKRD20A17P | ANKRD20A18P | ANKRD20A19P | ANKRD20A2P | ANKRD20A3P | ANKRD20A4-ANKRD20A20P | ANKRD20A4P | ANKRD20A5P | ANKRD20A8P | ANKRD20A9P | ANKRD22 | ANKRD23 | ANKRD24 | ANKRD26 | ANKRD26P1 | ANKRD26P3