Understanding The Potential of NKCC2 as A Cancer Drug Target and Biomarker

Target Name: SLC12A1

NCBI ID: G6557

SLC12A1

Understanding The Potential of NKCC2 as A Cancer Drug Target and Biomarker

SLC12A1 (NKCC2) is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. The gene is located on chromosome 12 and encodes a protein known as NKCC2. NKCC2 is a transmembrane protein that is involved in several cellular processes, including cell signaling, DNA repair, and cell adhesion.

Several studies have identified NKCC2 as a potential drug target due to its involvement in various diseases, including cancer. For example, studies have shown that high levels of NKCC2 have been observed in various types of cancer, such as breast cancer, lung cancer, and colon cancer. Additionally, NKCC2 has been shown to promote the growth and survival of cancer cells, which could make it an attractive target for cancer treatments.

In addition to its potential as a drug target, NKCC2 has also been identified as a potential biomarker for cancer. The protein is expressed in various tissues and cells, including the bloodstream, lymph nodes, and cancer cells. Additionally, NKCC2 has been shown to be downregulated in cancer cells, which could make it an attractive target for cancer diagnostics and treatments.

Despite the potential benefits of NKCC2 as a drug target and biomarker, further research is needed to fully understand its role in cancer. One of the main challenges in studying NKCC2 is its complex structure and the difficulty in manipulating its levels in live cells. However, researchers are actively working to overcome these challenges and to fully understand the potential of NKCC2 as a drug target and biomarker.

In conclusion, SLC12A1 (NKCC2) is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand its role in cancer and to develop effective treatments. By targeting NKCC2, researchers hope to improve cancer treatment outcomes and advance the field of cancer research.

Protein Name: Solute Carrier Family 12 Member 1

Functions: Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system

The "SLC12A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC12A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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