CYP4V2: A Potential Drug Target Or Biomarker (G285440)

Target Name: CYP4V2

NCBI ID: G285440

CYP4V2

CYP4V2: A Potential Drug Target Or Biomarker

CYP4V2 (Cytochrome P450 family 4 subfamily V member 2) is a gene that encodes a protein known as CYP4V2. CYP4V2 is a member of the cytochrome P450 (CYP) family, which is a large gene family that plays a central role in the metabolism of various drugs and other molecules. The CYP4V2 gene is located on chromosome 19 at position 6.2 and encodes a protein with 483 amino acid residues.

The CYP4V2 gene is a potential drug target or biomarker because it is involved in the metabolism of many drugs, including statins, antidepressants, and opioids. The metabolism of these drugs by CYP4V2 can be affected by genetic variations, which can result in differences in the amount of the drug that is metabolized and the rate at which it is cleared from the body. Therefore, studies have suggested that CYP4V2 may be a useful biomarker for monitoring the effectiveness of drugs that are used to treat various psychiatric and neurological disorders.

In addition to its potential as a drug target, CYP4V2 has also been shown to be involved in the regulation of other physiological processes in the body. For example, studies have shown that CYP4V2 is involved in the metabolism of xenobiotics, which are drugs that are used to treat a wide range of diseases and disorders. Xenobiotics can have both beneficial and detrimental effects on the body, and the metabolism of these drugs by CYP4V2 can play a crucial role in determining their efficacy or potential harm.

Another potential application of CYP4V2 as a drug target is its role in the regulation of cellular signaling pathways. Many drugs that are used to treat various diseases work by modulating the activity of signaling pathways, which are the networks of chemical reactions that occur within cells. CYP4V2 is involved in the metabolism of many drugs that are used to treat psychiatric and neurological disorders, including many statins, which are used to treat high cholesterol. Therefore, studies have suggested that CYP4V2 may be a useful target for drugs that are used to treat these disorders.

In conclusion, CYP4V2 is a gene that encodes a protein that is involved in the metabolism of many drugs and other molecules. Its potential as a drug target or biomarker makes it an attractive target for researchers who are seeking to develop new treatments for various psychiatric and neurological disorders. Further research is needed to fully understand the role of CYP4V2 in the regulation of drug metabolism and other physiological processes in the body.

Protein Name: Cytochrome P450 Family 4 Subfamily V Member 2

Functions: A cytochrome P450 monooxygenase involved in fatty acid metabolism in the eye. Catalyzes the omega-hydroxylation of polyunsaturated fatty acids (PUFAs) docosahexaenoate (DHA) and its precursor eicosapentaenoate (EPA), and may contribute to the homeostasis of these retinal PUFAs (PubMed:22772592). Omega hydroxylates saturated fatty acids such as laurate, myristate and palmitate, the catalytic efficiency decreasing in the following order: myristate > laurate > palmitate (C14>C12>C16) (PubMed:19661213). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)

The "CYP4V2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CYP4V2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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