FHOD1: A Potential Drug Target and Biomarker (G29109)

Target Name: FHOD1

NCBI ID: G29109

FHOD1

FHOD1: A Potential Drug Target and Biomarker

Factor HIF1A (FHOD1), a key regulator of the unfolded protein response (FDR), has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in the regulation of protein stability and dynamics has been studied extensively in the past decade, and its potential as a drug target has led to a growing interest in the development of compounds that can modulate FHIF1A activity. In this article, we will discuss the biology of FHOD1, its potential as a drug target, and the ongoing research in this field.

The FHIF1A gene is located on chromosome 16 and encodes a protein that plays a critical role in the regulation of protein stability and dynamics. FHIF1A functions as a scaffold protein that interacts with various partner proteins to control the assembly, stability, and degradation of other proteins. It does this by playing a key role in the formation of a protein-protein interaction network, known as the FHIF1A-regulated complex (FRC), which is responsible for the regulation of protein stability and dynamics.

FHIF1A has been shown to play a critical role in the regulation of various proteins, including transcription factors, stress proteins, and cytoskeletal components. It has been shown to interact with numerous protein partners, including casein kinase (CK) 2, heat shock protein (HSP) 70, and myosin ATPase. FHIF1A has also been shown to play a key role in the regulation of protein stability and dynamics, by controlling the formation and stability of various protein species.

FHOD1 has been identified as a potential drug target due to its unique mechanism of action and its involvement in various diseases. FHOD1 is a protein that can modulate the activity of other proteins, making it a potential target for drugs that aim to modulate protein function. Its role in the regulation of protein stability and dynamics also makes it an attractive target for drugs that aim to modulate protein stability.

In cancer, FHOD1 has been shown to play a critical role in the regulation of various protein interactions, including the regulation of cell cycle progression and the regulation of apoptosis. It has also been shown to interact with various transcription factors, including p53, to control the expression of pro-inflammatory genes. Therefore, inhibiting FHOD1 activity may be a promising strategy for the treatment of cancer.

In neurodegenerative diseases, FHOD1 has been shown to play a critical role in the regulation of various protein interactions, including the regulation of neurotransmitter release and the regulation of synaptic plasticity. Its involvement in these processes makes it an attractive target for drugs that aim to treat neurodegenerative diseases.

In autoimmune disorders, FHOD1 has been shown to play a critical role in the regulation of various protein interactions, including the regulation of immune cell function and the regulation of inflammation. Therefore, modulating FHOD1 activity may be a promising strategy for the treatment of autoimmune disorders.

In conclusion, FHOD1 is a protein that has the potential to be a drug target and biomarker for various diseases. Its role in the regulation of protein stability and dynamics, as well as its involvement in various diseases, make it an attractive target for the development of new treatments. Further research is needed to fully understand the biology of FHOD1 and its potential as a drug target.

Protein Name: Formin Homology 2 Domain Containing 1

Functions: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing

The "FHOD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FHOD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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