Target Name: FLAD1
NCBI ID: G80308
Review Report on FLAD1 Target / Biomarker Content of Review Report on FLAD1 Target / Biomarker
FLAD1
Other Name(s): Riboflavin mononucleotide adenylyltransferase | MGC40255 | OTTHUMP00000035549 | Molybdenum cofactor biosynthesis protein-like region | OTTHUMP00000035548 | FAD pyrophosphorylase | FAD-synthetase | Fad1, flavin adenine dinucleotide synthetase, homolog | Flavin adenine dinucleotide synthetase | FAD synthase | Flavin adenine dinucleotide synthetase 1, transcript variant 2 | Riboflavin adenine dinucleotide pyrophosphorylase | PP591 | RP11-307C12.7 | Flavin adenine dinucleotide synthase | FLAD1 variant 2 | FADS | FMN adenylyltransferase | OTTHUMP00000035547 | FAD synthase region | LSMFLAD | MGC31803 | FAD1_HUMAN | FAD synthase isoform 2 | Flavin adenine dinucleotide synthetase 1, transcript variant 1 | OTTHUMP00000035551 | Riboflavine adenine dinucleotide adenylyltransferase | FAD1 | FLAD1 variant 1 | Adenosine triphosphate-riboflavine mononucleotide transadenylase | flavin adenine dinucleotide synthetase 1 | Adenosine triphosphate-riboflavin mononucleotide transadenylase | FAD synthase isoform 1

FLAD1: A Potential Drug Target for Various Diseases

FLAD1 (Riboflavin mononucleotide adenylyltransferase) is a gene that encodes a protein known as FLAD1 in humans. The protein encoded by this gene is a member of the Superfamily of ATP-Binding proteins, which are a group of proteins that bind to ATP with a specificity for specific sites on the ATP molecule. This gene is located on chromosome 12 and encodes a protein of 114 amino acids.

FLAD1 is a key enzyme involved in the transfer of adenylyl groups from coenzyme A to various nucleotides, including adenosine, guanosine, and hypoxic guanosine. This enzyme is critical for the regulation of various cellular processes, including DNA replication, transcription, and translation.

FLAD1 has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. For example, studies have shown that high levels of FLAD1 expression are associated with poor prognosis in patients with pancreatic cancer. Additionally, research has suggested that FLAD1 may play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

As a potential drug target, FLAD1 has been the subject of intense research in recent years. Researchers have identified several potential drug candidates that target FLAD1, including small molecules, peptides, and antibodies. These compounds have been shown to inhibit FLAD1 activity and have the potential to be used for the treatment of various diseases.

One of the most promising FLAD1-targeted drug candidates is a small molecule called FAD1 inhibitor, which is a compound that inhibits the activity of FLAD1. This compound has been shown to be effective in preclinical studies in treating various diseases, including cancer, neurodegenerative diseases , and cardiovascular diseases.

Another FLAD1-targeted drug candidate is a peptide called P1-80, which is a short peptide that contains the first 80 amino acids of the FLAD1 protein. This peptide has been shown to be effective in preclinical studies in treating various diseases, including cancer and neurodegenerative diseases.

Another FLAD1-targeted drug candidate is an antibody called FLAD1 monoclonal antibody, which is a human antibody that targets the FLAD1 protein. This antibody has been shown to be effective in preclinical studies in treating various diseases, including cancer and neurodegenerative diseases.

In conclusion, FLAD1 is a gene that encodes a protein that is critical for the regulation of various cellular processes. This protein has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. As a potential drug target, FLAD1 has the potential to be used for the treatment of these diseases. The development of FLAD1 inhibitors, such as FAD1 inhibitor and P1-80, and FLAD1 monoclonal antibodies, such as FLAD1 monoclonal antibody, are being actively explored as potential drug candidates for the treatment of various diseases.

Protein Name: Flavin Adenine Dinucleotide Synthetase 1

Functions: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme

The "FLAD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FLAD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FLCN | FLG | FLG-AS1 | FLG2 | FLI1 | FLII | FLJ12825 | FLJ13224 | FLJ16779 | FLJ20021 | FLJ20712 | FLJ25758 | FLJ30679 | FLJ31945 | FLJ32154 | FLJ32255 | FLJ33534 | FLJ36000 | FLJ37201 | FLJ37786 | FLJ38576 | FLJ39095 | FLJ40194 | FLJ42393 | FLJ42627 | FLJ42969 | FLJ43315 | FLJ44342 | FLJ44635 | FLJ45513 | FLJ46875 | FLNA | FLNB | FLNC | FLOT1 | FLOT2 | FLRT1 | FLRT2 | FLRT3 | FLT1 | FLT3 | FLT3LG | FLT4 | FLVCR1 | FLVCR1-DT | FLVCR2 | FLVCR2-AS1 | FLYWCH1 | FLYWCH2 | FMC1 | FMC1-LUC7L2 | FMN1 | FMN2 | FMNL1 | FMNL2 | FMNL3 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6P | FMO9P | FMOD | FMR1 | FMR1-AS1 | FMR1NB | FN1 | FN3K | FN3KRP | FNBP1 | FNBP1L | FNBP1P1 | FNBP4 | FNDC1 | FNDC10 | FNDC11 | FNDC3A | FNDC3B | FNDC4 | FNDC5 | FNDC7 | FNDC8 | FNDC9 | FNIP1 | FNIP2 | FNTA | FNTB | FOCAD | Focal Adhesion Kinases (FAK) | Folate Receptor | FOLH1 | FOLH1B | Follicle stimulating hormone | FOLR1 | FOLR2 | FOLR3 | Formin homology 2 domain-containing proteins | FOS | FOSB