Target Name: FIRRE
NCBI ID: G286467
Review Report on FIRRE Target / Biomarker Content of Review Report on FIRRE Target / Biomarker
FIRRE
Other Name(s): FIRRE variant 1 | LINC01200 | firre intergenic repeating RNA element | Firre intergenic repeating RNA element, transcript variant 1

FIRRE: A Gene Expression Implicated in Disease Development

FIRRE (Fireside inverse rectifier) 鈥嬧?媔s a unique gene expression in the human body that has not been previously identified. It has been found to be highly expressed in various tissues and has been associated with several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders . The function and significance of FIRRE is still being explored, but it is clear that it plays an important role in the development and progression of these diseases.

FIRRE is a gene that encodes a protein known as the inverse rectifier protein (IRP). The IRP is a transmembrane protein that is involved in a variety of physiological processes, including cell signaling, ion channels, and voltage-dependent gene transcription. It is well established that FIRRE is involved in the regulation of cell proliferation and has been implicated in the development and progression of several diseases.

One of the key functions of the IRP is its ability to regulate the activity of ion channels, which are critical for the rapid and efficient transmission of electrical signals through the cell membrane. The IRP has been shown to play a role in the regulation of ion channels, including the sodium (Na+) and calcium (Ca2+) channels. These channels are involved in a variety of physiological processes, including muscle contractions, nerve signaling, and brain function.

In addition to its role in ion channels, the IRP is also involved in the regulation of gene transcription. It has been shown to play a role in the development and progression of cancer by regulating the activity of oncogenes and tumor suppressors. has been implicated in the regulation of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases, by modulating the activity of neural cell lines and animal models of these diseases.

FIRRE has also been shown to play a role in the regulation of inflammation. It has been shown to be involved in the regulation of immune cell function and the production of pro-inflammatory cytokines. This involvement in inflammation may contribute to the role of FIRRE in the development and progression of autoimmune disorders.

Despite the clear involvement of FIRRE in several physiological processes, the precise function and mechanism of its expression is not yet fully understood. Several studies have investigated the role of FIRRE in various cellular and biological processes, but the results have been inconsistent. More research is needed to fully understand the function and significance of FIRRE and to explore its potential as a drug target or biomarker.

Targeting FIRRE

The potential target of FIRRE makes it an attractive candidate for drug development. Given its involvement in multiple physiological processes, it is possible that FIRRE could be targeted by small molecules or other therapeutic agents that can modulate its activity.

One approach to targeting FIRRE is to use small molecules that can modulate the activity of ion channels. Drugs that have been shown to modulate ion channels in cell lines or animal models of disease may be effective in targeting FIRRE. For example, drugs that can inhibit the activity of sodium channels, such as amilorlecilevulinic acid (AML), have been shown to be effective in the treatment of hypertension and other cardiovascular diseases. It is possible that these drugs could also be effective in targeting FIRRE.

Another approach to targeting FIRRE is to use antibodies or other proteins that can specifically recognize and target it. This approach has been used to target various proteins involved in the development and progression of cancer, including Her2, PD-L1, and NF-kappa-B. By using antibodies or other proteins that can recognize and target FIRRE, it may be possible to block its activity and prevent the development and progression of disease.

In addition to these direct approaches, it is also important to consider the potential role of FIRRE as a biomarker in the diagnosis and treatment of disease. By identifying biomarkers that are associated with the expression of FIRRE, it may be possible to develop diagnostic tests or therapeutic approaches that target FIRRE and improve treatment outcomes. For example, if FIRRE is associated with the development of neurodegenerative diseases, then identifying biomarkers that are specific to these diseases may be valuable for the diagnosis and treatment of these conditions.

Conclusion

In conclusion, FIRRE is a gene expression that has not been previously identified. It is involved in the regulation of ion channels, gene transcription, and inflammation, and has been implicated in the development and progression of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The potential target of FIRRE makes it an attractive candidate for drug development, and a variety of approaches, including small molecules and antibodies, may be effective in targeting and modulating its activity. Further research is needed to fully understand the function and significance of FIRRE and to explore its potential as a drug target or biomarker.

Protein Name: Firre Intergenic Repeating RNA Element

The "FIRRE Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FIRRE comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FIS1 | FITM1 | FITM2 | Five friends of methylated CHTOP complex | FIZ1 | FJX1 | FKBP10 | FKBP11 | FKBP14 | FKBP15 | FKBP1A | FKBP1A-SDCBP2 | FKBP1B | FKBP1C | FKBP2 | FKBP3 | FKBP4 | FKBP5 | FKBP6 | FKBP7 | FKBP8 | FKBP9 | FKBP9P1 | FKBPL | FKRP | FKSG29 | FKTN | FLACC1 | FLAD1 | FLCN | FLG | FLG-AS1 | FLG2 | FLI1 | FLII | FLJ12825 | FLJ13224 | FLJ16779 | FLJ20021 | FLJ20712 | FLJ25758 | FLJ30679 | FLJ31945 | FLJ32154 | FLJ32255 | FLJ33534 | FLJ36000 | FLJ37201 | FLJ37786 | FLJ38576 | FLJ39095 | FLJ40194 | FLJ42393 | FLJ42627 | FLJ42969 | FLJ43315 | FLJ44342 | FLJ44635 | FLJ45513 | FLJ46875 | FLNA | FLNB | FLNC | FLOT1 | FLOT2 | FLRT1 | FLRT2 | FLRT3 | FLT1 | FLT3 | FLT3LG | FLT4 | FLVCR1 | FLVCR1-DT | FLVCR2 | FLVCR2-AS1 | FLYWCH1 | FLYWCH2 | FMC1 | FMC1-LUC7L2 | FMN1 | FMN2 | FMNL1 | FMNL2 | FMNL3 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6P | FMO9P | FMOD | FMR1 | FMR1-AS1 | FMR1NB | FN1 | FN3K | FN3KRP | FNBP1