FLJ37786: A Potential Drug Target and Biomarker (G642691)

Target Name: FLJ37786

NCBI ID: G642691

FLJ37786

Other Name(s): Uncharacterized LOC642691

FLJ37786: A Potential Drug Target and Biomarker

FLJ37786 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its unique structure and subcellular localization have led to its potential as a drug target. The protein is composed of 254 amino acids and has a calculated molecular weight of 30 kDa. It is expressed in the brain and other tissues at levels ranging from 1 to 10 mg/g of muscle protein.

FLJ37786 has been shown to play a role in several physiological processes in the body, including cell signaling, neurotransmitter release, and inflammation. Its expression has also been linked to several diseases, including neurodegenerative disorders, chronic kidney disease, and diabetes.

One of the most promising aspects of FLJ37786 is its potential as a drug target. The protein is known to interact with several intracellular signaling pathways, including the TGF-β pathway and the NF-kappa-B pathway. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and inflammation.

FLJ37786 has also been shown to interact with several kinases, including Src, FAK, and PDGFR. These kinases are involved in the production of extracellular signaling molecules, such as tyrosine and phosphatidylinositol. The interaction of FLJ37786 with these kinases suggests that it may be a useful target for small molecule inhibitors.

In addition to its potential as a drug target, FLJ37786 has also been shown to be a potential biomarker for several diseases. Its expression has been linked to the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the progression of chronic kidney disease and type 2 diabetes.

The potential utility of FLJ37786 as a drug target is further underscored by its unique subcellular localization. Unlike many other proteins, FLJ37786 is primarily expressed in the brain and other tissues, rather than in the muscle or other body tissues. This suggests that it may be targeted by small molecules that are selectively distributed to these specific tissues.

FLJ37786 has also been shown to play a role in several cellular processes that are important for maintaining cellular homeostasis. Its expression has been linked to the production of several stress response proteins, including heat shock proteins and autophagy-related proteins. These proteins are involved in monitoring and correcting cellular stress, which is critical for maintaining cellular homeostasis.

In conclusion, FLJ37786 is a protein that has the potential to be a drug target and biomarker. Its unique structure and subcellular localization, as well as its involvement in several physiological processes and its expression in the brain and other tissues, make it an attractive target for small molecule inhibitors. Further research is needed to determine the full potential of FLJ37786 as a drug and biomarker.

Protein Name: Uncharacterized LOC642691

The "FLJ37786 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FLJ37786 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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