Target Name: FKBP6
NCBI ID: G8468
Review Report on FKBP6 Target / Biomarker Content of Review Report on FKBP6 Target / Biomarker
FKBP6
Other Name(s): inactive PPIase FKBP6 | 36 kDa FK506-binding protein | SPGF77 | immunophilin FKBP36 | FKBP prolyl isomerase family member 6 (inactive), transcript variant 2 | FKBP36 | peptidyl-prolyl cis-trans isomerase FKBP6 | FKBP6_HUMAN | FK506-binding protein 6 | Rotamase | FKBP6 variant 1 | Inactive PPIase FKBP6 | rotamase | FK506 binding protein 6 (FKBP6) | Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (isoform b) | 36 kDa FKBP | Immunophilin FKBP36 | FKBP prolyl isomerase family member 6 (inactive), transcript variant 1 | FKBP prolyl isomerase family member 6 (inactive) | PPIase | FK506 binding protein 6, 36kDa | FKBP prolyl isomerase 6 | FKBP-6 | FKBP-36 | Inactive peptidyl-prolyl cis-trans isomerase FKBP6 | FKBP6 variant 2 | Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (isoform a) | PPIase FKBP6

FKBP6: A Potential Drug Target and Biomarker

FKBP6 (6-furanylated ketopurine) is a medication that is used to treat autoimmune disorders, such as rheumatoid arthritis, lupus, and progressive multiple sclerosis. It works by inhibiting the activity of a protein called PPIase FKBP6, which is an enzyme that is involved in the breakdown of certain medications, including chemotherapy drugs.

FPKBP6, also known as furanylated ketopurine, is an inhibitor of PPIase FKBP6, which is an enzyme involved in the metabolism of chemotherapy drugs.

The FKBP6 enzyme plays a crucial role in the regulation of cellular processes that are essential for the growth, division, and survival of cells. One of its primary functions is to regulate the levels of certain chemotherapy drugs, which are often used to treat cancer. However, some chemotherapy drugs can cause damage to the cells if they are not properly metabolized. This is where FKBP6 comes in. By inhibiting the activity of PPIase FKBP6, FKBP6 can help to reduce the risk of cancer cells developing resistance to these drugs.

FPKBP6 is also a potent biomarker for cancer. The levels of FKBP6 in cancer cells can be used as a marker for the presence and extent of cancer. This is because FKBP6 is often expressed in high levels in cancer cells, and can be used as a target for cancer therapies.

In addition to its potential as a cancer biomarker, FKBP6 may also be a drug target. By inhibiting the activity of PPIase FKBP6, FKBP6 can potentially be used to treat a variety of diseases that are caused by the over-activity of this enzyme.

FPKBP6 is currently being studied as a potential drug target and biomarker in a variety of clinical trials. For example, some researchers are exploring the potential of FKBP6 as a treatment for multiple sclerosis, an autoimmune disorder that affects millions of people around the world.

In addition to its potential use as a drug and biomarker, FKBP6 is also of interest to researchers because of its unique structure. Unlike many other proteins, FKBP6 is not natural and is instead a synthetic compound that was designed to be used as an inhibitor of PPIase FKBP6. This makes it a valuable tool for researchers to study the biology of this enzyme and its role in the development of disease.

In conclusion, FKBP6 is a medication that is currently being used to treat autoimmune disorders and is also being studied as a potential drug target and biomarker. Its unique structure and ability to inhibit the activity of PPIase FKBP6 make it an attractive candidate for further research. As research continues, it is likely that we will learn even more about the role of FKBP6 in the treatment of disease and the development of new treatments.

Protein Name: FKBP Prolyl Isomerase Family Member 6 (inactive)

Functions: Has an essential role in spermatogenesis (PubMed:36150389). It is required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity). Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis (By similarity). May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity)

The "FKBP6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FKBP6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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FKBP7 | FKBP8 | FKBP9 | FKBP9P1 | FKBPL | FKRP | FKSG29 | FKTN | FLACC1 | FLAD1 | FLCN | FLG | FLG-AS1 | FLG2 | FLI1 | FLII | FLJ12825 | FLJ13224 | FLJ16779 | FLJ20021 | FLJ20712 | FLJ25758 | FLJ30679 | FLJ31945 | FLJ32154 | FLJ32255 | FLJ33534 | FLJ36000 | FLJ37201 | FLJ37786 | FLJ38576 | FLJ39095 | FLJ40194 | FLJ42393 | FLJ42627 | FLJ42969 | FLJ43315 | FLJ44342 | FLJ44635 | FLJ45513 | FLJ46875 | FLNA | FLNB | FLNC | FLOT1 | FLOT2 | FLRT1 | FLRT2 | FLRT3 | FLT1 | FLT3 | FLT3LG | FLT4 | FLVCR1 | FLVCR1-DT | FLVCR2 | FLVCR2-AS1 | FLYWCH1 | FLYWCH2 | FMC1 | FMC1-LUC7L2 | FMN1 | FMN2 | FMNL1 | FMNL2 | FMNL3 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6P | FMO9P | FMOD | FMR1 | FMR1-AS1 | FMR1NB | FN1 | FN3K | FN3KRP | FNBP1 | FNBP1L | FNBP1P1 | FNBP4 | FNDC1 | FNDC10 | FNDC11 | FNDC3A | FNDC3B | FNDC4 | FNDC5 | FNDC7 | FNDC8 | FNDC9 | FNIP1 | FNIP2 | FNTA | FNTB | FOCAD | Focal Adhesion Kinases (FAK)