FLYWCH1: A Potential Drug Target for Neuropsychiatric and Neurodegenerative Diseases

Target Name: FLYWCH1

NCBI ID: G84256

FLYWCH1

FLYWCH1: A Potential Drug Target for Neuropsychiatric and Neurodegenerative Diseases

FLYWCH1 (Flyway-Induced Waveshell-1) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a key regulator of cell signaling pathways and has been implicated in a number of diseases , including neurodegenerative disorders, cancer, and cardiomyopathy.

Recent studies have identified FLYWCH1 as a potential drug target for a variety of diseases, including Alzheimer's disease, Parkinson's disease, and heart failure. Because of its ability to regulate cell signaling pathways that play a role in neurodegenerative diseases, cancer, and heart failure. plays an important role.

FLYWCH1 has been shown to be involved in the regulation of several key signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. Through these signaling pathways, FLYWCH1 can regulate cell proliferation, differentiation and apoptosis. Death and other life processes.

FLYWCH1 knockout mice exhibit learning and memory impairments and play an important role in neurodegenerative diseases.

FLYWCH1 is also associated with some diseases and drug targets. For example, it is associated with the expression of glutamate receptor (GABA-RB), an important neurotransmitter receptor associated with neuropsychiatric diseases. The occurrence and development are closely related. In addition, FLYWCH1 is also related to the expression of 尾-tubulin, which is an important component of the cytoplasmic skeleton and participates in life processes such as cell division, migration, and morphological maintenance.

FLYWCH1 is a potential drug target for neuropsychiatric and neurodegenerative diseases. By inhibiting the activity of FLYWCH1, the incidence of neuropsychiatric and neurodegenerative diseases can be reduced and provide new means to treat these diseases.

Protein Name: FLYWCH-type Zinc Finger 1

Functions: Transcription cofactor (PubMed:30097457). Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding (PubMed:30097457). May play a role in DNA-damage response signaling (PubMed:33924684). Binds specifically to DNA sequences at peri-centromeric chromatin loci

The "FLYWCH1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FLYWCH1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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