Target Name: HMMR
NCBI ID: G3161
Review Report on HMMR Target / Biomarker Content of Review Report on HMMR Target / Biomarker
HMMR
Other Name(s): CD168 | Hyaluronan mediated motility receptor (isoform d) | OTTHUMP00000196920 | OTTHUMP00000224276 | Hyaluronan mediated motility receptor, transcript variant 1 | Hyaluronan mediated motility receptor (isoform b) | Intracellular hyaluronic acid-binding protein | hyaluronan mediated motility receptor | HMMR_HUMAN | OTTHUMP00000160919 | OTTHUMP00000224277 | HMMR variant 2 | RHAMM | HMMR variant 4 | intracellular hyaluronic acid-binding protein | HMMR variant 3 | OTTHUMP00000160920 | Hyaluronan mediated motility receptor, transcript variant 2 | MGC119494 | MGC119495 | Hyaluronan mediated motility receptor, transcript variant 3 | Hyaluronan mediated motility receptor, transcript variant 4 | Receptor for hyaluronan-mediated motility | IHABP | Hyaluronan mediated motility receptor | Hyaluronan mediated motility receptor (isoform a) | Hyaluronan mediated motility receptor (isoform c) | receptor for hyaluronan-mediated motility | HMMR variant 1

HMMR: A Potential Drug Target for Cellular Stress and Cancer

HMMR (CD168), a protein that belongs to the heat shock protein (HSP) family, is a key regulator of cellular stress responses and has been identified as a potential drug target in various diseases, including cancer.

HMMR is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, liver, and muscle. It is involved in the regulation of protein folding and localization, as well as in the detoxification of oxidative stress.

Recent studies have suggested that HMMR plays a crucial role in the pathogenesis of several diseases, including cancer. For example, it has been shown to be overexpressed in various types of cancer, and to contribute to the development of cancer-induced neurodegeneration.

In addition to its potential role in cancer, HMMR has also been suggested as a potential drug target for treating a variety of other diseases. For example, it has been shown to be involved in the regulation of inflammation, and to play a role in the development of autoimmune diseases.

HMMR is also a good candidate for a potential drug target because of its unique structure and its ability to interact with a variety of different molecules. This makes it a promising target for small molecules, as well as for drugs that target other proteins.

In conclusion, HMMR is a protein that has the potential to be a drug target for a variety of diseases. Further research is needed to fully understand its role in the regulation of cellular stress responses and to develop effective treatments for diseases that are caused by its dysfunction.

Protein Name: Hyaluronan Mediated Motility Receptor

Functions: Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity)

The "HMMR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HMMR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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HMOX1 | HMOX2 | HMSD | HMX1 | HMX2 | HNF1A | HNF1A-AS1 | HNF1B | HNF4A | HNF4G | HNF4GP1 | HNMT | HNRNPA0 | HNRNPA1 | HNRNPA1L2 | HNRNPA1L3 | HNRNPA1P10 | HNRNPA1P12 | HNRNPA1P16 | HNRNPA1P2 | HNRNPA1P21 | HNRNPA1P27 | HNRNPA1P33 | HNRNPA1P35 | HNRNPA1P36 | HNRNPA1P39 | HNRNPA1P41 | HNRNPA1P5 | HNRNPA1P51 | HNRNPA1P6 | HNRNPA1P60 | HNRNPA1P7 | HNRNPA1P70 | HNRNPA2B1 | HNRNPA3 | HNRNPA3P1 | HNRNPA3P6 | HNRNPAB | HNRNPC | HNRNPCL1 | HNRNPCL2 | HNRNPCL3 | HNRNPCP1 | HNRNPD | HNRNPDL | HNRNPF | HNRNPH1 | HNRNPH2 | HNRNPH3 | HNRNPK | HNRNPKP1 | HNRNPKP2 | HNRNPKP3 | HNRNPKP4 | HNRNPL | HNRNPLL | HNRNPM | HNRNPR | HNRNPU | HNRNPU antisense RNA 1 | HNRNPUL1 | HNRNPUL2 | HNRNPUL2-BSCL2 | HOATZ | HOGA1 | Homeodomain-interacting protein kinase | HOMER1 | HOMER2 | HOMER2P1 | HOMER3 | HOMEZ | HOOK1 | HOOK2 | HOOK3 | Hop2-Mnd1 complex | HOPX | HORMAD1 | HORMAD2 | HORMAD2-AS1 | HOTAIR | HOTAIRM1 | HOTTIP | HOXA-AS2 | HOXA-AS3 | HOXA1 | HOXA10 | HOXA10-AS | HOXA10-HOXA9 | HOXA11 | HOXA11-AS | HOXA13 | HOXA2 | HOXA3 | HOXA4 | HOXA5 | HOXA6 | HOXA7 | HOXA9 | HOXB-AS1 | HOXB-AS3