INHA: A Protein Targeted for Neuro-Oncology (G3623)

Target Name: INHA

NCBI ID: G3623

INHA

INHA: A Protein Targeted for Neuro-Oncology

INHA, or Inhibin alpha C subunit, is a protein that is expressed in various tissues throughout the body. It is a key component of the inhibin system, which is a regulatory mechanism that helps to maintain tissue homeostasis and prevent excessive cell growth. INHA has been identified as a potential drug target and is the focus of ongoing research in the field of neuro-oncology.

The inhibin system is a complex protein that is composed of two subunits: INH伪 and INH尾. INH伪 is the catalytic subunit, while INH尾 is the non-catalytic subunit. The INHA protein is a 14-kDa protein that is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract. It is highly homogeneous and has a single transmembrane domain.

INHA is involved in the regulation of cell growth, differentiation, and survival. It has been shown to play a role in the development and progression of various neuro-inflammatory diseases, including Alzheimer's disease, Parkinson's disease, and neuro-fibromatosis. INHA has also been shown to be involved in the regulation of pain perception and neuropeptide signaling.

As a potential drug target, INHA has been the focus of extensive research in the field of neuro-oncology. Researchers are interested in using INHA as a target for small molecule inhibitors that can modulate its activity and trigger neuro-oncogenic processes. This is because INHA has been shown to play a role in the development and progression of various neuro-inflammatory diseases, and small molecule inhibitors have the potential to selectively target its activity while minimizing the effects on other cell signaling pathways.

One approach that researchers have used to study INHA is to use RNA interference (RNAi) technology. RNAi is a technique that allows researchers to knockdown gene expression in specific cells or tissues, which can be useful for studying the role of INHA in various biological processes. Researchers have used RNAi to knockdown INHA expression in various cell types and have found that INHA is involved in the development and progression of various neuro-inflammatory diseases.

Another approach that researchers have used to study INHA is to use small molecule inhibitors. Researchers have synthesized a variety of small molecules that can modulate INHA activity and have found that some of these compounds are effective in inhibiting INHA-mediated neuro-oncogenic processes. These small molecules have the potential to be useful lead compounds for new neuro-oncology therapies.

In addition to its potential as a drug target, INHA is also a potential biomarker for various neuro-inflammatory diseases. The inhibin system has been shown to be involved in the regulation of pain perception and neuropeptide signaling, which may be useful for the diagnosis and prognosis of neuro-inflammatory diseases. Researchers have also shown that INHA is expressed in various tissues and may be a useful biomarker for monitoring the effectiveness of neuro-oncology therapies.

Overall, INHA is a protein that is involved in the inhibin system and has been shown to play a role in the development and progression of various neuro-inflammatory diseases. As a potential drug target and biomarker, INHA is the focus of ongoing research in the field of neuro-oncology and has the potential to lead to new and effective therapies for the treatment of neuro-inflammatory diseases.

Protein Name: Inhibin Subunit Alpha

Functions: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins

The "INHA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about INHA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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