Target Name: LAMTOR4
NCBI ID: G389541
Review Report on LAMTOR4 Target / Biomarker Content of Review Report on LAMTOR4 Target / Biomarker
LAMTOR4
Other Name(s): LTOR4_HUMAN | LAMTOR4 variant 1 | Ragulator complex protein LAMTOR4 | C7orf59 | late endosomal/lysosomal adaptor and MAPK and MTOR activator 4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4, transcript variant 1 | MGC163425 | MGC163431 | Ragulator complex protein LAMTOR4, N-terminally processed | UPF0539 protein C7orf59 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | Ragulator complex protein LAMTOR4 (isoform 1) | Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4

LAMTOR4: A Potential Drug Target for TOR Signaling and Cellular Processes

LAMTOR4 (also known as LTOR4_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and skeletal muscles. It is a key regulator of the Luggage (TOR) signaling pathway, which is a well- established network that regulates cell growth, metabolism, and survival. LAMTOR4 plays a crucial role in this pathway by regulating the activity of the protein p70, which is a key component of the TOR complex.

The TOR signaling pathway is a well-established network that regulates various cellular processes in the cell, including cell growth, metabolism, and stress response. The TOR complex is a key component of this pathway, as it consists of the protein p70, which is a key regulator of the pathway, as well as several other proteins that play various roles in regulating cellular processes.

One of the functions of LAMTOR4 is to regulate the activity of p70. This is done through a process called phosphorylation, which involves the addition of a phosphate group to the protein. This phosphorylation process is critical for the activity of LAMTOR4, as it allows it to interact with p70 and regulate its activity.

In addition to regulating p70 activity, LAMTOR4 also plays a role in the regulation of cellular processes that are not directly related to the TOR signaling pathway. For example, LAMTOR4 has been shown to play a role in the regulation of cell adhesion, which is the process by which cells stick together and form tissues.

The LAMTOR4 gene is located on chromosome 18 and has been shown to play a role in the development and maintenance of various tissues in the body. For example, studies have shown that LAMTOR4 is highly expressed in the brain, heart, and skeletal muscles, and that it is involved in the regulation of cellular processes that are critical for these tissues.

In addition to its role in the regulation of cellular processes, LAMTOR4 is also a potential drug target. Several studies have shown that LAMTOR4 is a promising target for the development of new therapies for various diseases, including cancer, neurodegenerative diseases, and metabolic disorders.

One of the reasons why LAMTOR4 is considered a promising drug target is its involvement in the regulation of cellular processes that are critical for the development and maintenance of various tissues in the body. This makes it a potential target for the development of new therapies that can treat a wide range of diseases.

Another reason why LAMTOR4 is considered a promising drug target is its unique structure and biology. Unlike many other proteins, LAMTOR4 has a clear and well-defined function, which makes it easier to study and understand. This is important for the development of new drugs that can specifically target LAMTOR4 and its function.

Finally, LAMTOR4 is also a potential drug target because it has been shown to play a role in the regulation of various diseases, including cancer, neurodegenerative diseases, and metabolic disorders. This makes it a potential target for the development of new therapies that can treat these diseases.

In conclusion, LAMTOR4 is a protein that is expressed in various tissues of the human body and plays a crucial role in the regulation of the TOR signaling pathway. It is a potential drug target due to its unique structure and biology, its involvement in the regulation of cellular processes that are critical for the development and maintenance of various tissues, and its potential role in the regulation of various diseases. Further research is needed to fully understand the function and potential of LAMTOR4 as a drug target.

Protein Name: Late Endosomal/lysosomal Adaptor, MAPK And MTOR Activator 4

Functions: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated

The "LAMTOR4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LAMTOR4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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