GUCY2EP: A Potential Drug Target and Biomarker (G390226)
GUCY2EP: A Potential Drug Target and Biomarker
Gucy2EP, or G-protein-coupled receptor GPCR, is a protein that is expressed in various tissues and cells in the body. It is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling. GPCRs are involved in a wide range of physiological processes, including sensory perception, neurotransmission, and hormone signaling.
Gucy2EP has been identified as a potential drug target and biomarker due to its unique biology and the potential impact it could have on various diseases. In this article, we will explore the biology of Gucy2EP and its potential as a drug target, as well as its potential as a biomarker for certain diseases.
The GPCR family consists of over 700 different genes, with Gucy2EP being one of the most well-studied members. It is characterized by a extracellular domain that includes a catalytic alpha-helices and a transmembrane region. The transmembrane region of Gucy2EP is composed of four transmembrane domains: an N-terminal alpha-helix, a transmembrane segment, a second N-terminal alpha-helix, and a C-terminal alpha-helices.
Gucy2EP is a potent modulator of sensory signaling, particularly in the context of pain perception. It is expressed in the dorsal root of the spinal cord, which is the primary site of pain processing in the body. Gucy2EP is involved in the regulation of pain signaling by neurotransmitter release and cell-signaling pathways.
In addition to its role in pain perception, Gucy2EP is also a potential drug target for several psychiatric and neurological disorders. For example, Gucy2EP has been shown to be involved in the pathophysiology of major depressive disorder (MDD) and anxiety disorders. It is also involved in the regulation of neurotransmitter release in the brain, which could make it a potential target for treating neurodegenerative diseases such as Alzheimer's disease.
As a biomarker, Gucy2EP has been shown to be involved in several diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. For example, Gucy2EP has been shown to be involved in the development and progression of neurobladder cancer. It is also involved in the regulation of neurotransmitter release in the brain, which could make it a potential biomarker for this disease.
In conclusion, Gucy2EP is a protein that is involved in a wide range of physiological processes and has been identified as a potential drug target and biomarker for several diseases. Further research is needed to fully understand the biology of Gucy2EP and its potential as a drug and biomarker.
Protein Name: Guanylate Cyclase 2E, Pseudogene
The "GUCY2EP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GUCY2EP comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GUCY2F | GUCY2GP | GUF1 | GUK1 | GULOP | GULP1 | GUSB | GUSBP1 | GUSBP11 | GUSBP12 | GUSBP14 | GUSBP15 | GUSBP17 | GUSBP2 | GUSBP3 | GUSBP4 | GUSBP5 | GUSBP8 | GVINP1 | GVQW3 | GXYLT1 | GXYLT1P3 | GXYLT1P4 | GXYLT1P6 | GXYLT2 | GYG1 | GYG2 | GYPA | GYPB | GYPC | GYPE | GYS1 | GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8
