H2AC17: A Protein Targeted for Cancer Therapeutic Intervention and Biomarker
H2AC17: A Protein Targeted for Cancer Therapeutic Intervention and Biomarker
H2AC17, also known as HIST1H2AL, is a protein that is expressed in the hematopoietic stem cells (HSCs) and is involved in the development and maintenance of hematological malignancies, including leukemia. The H2AC17 gene was identified as a potential drug target in the field of cancer research and is currently being targeted for therapeutic intervention.
The H2AC17 protein is a member of the histone family, which plays a critical role in the regulation of gene expression and chromosomal stability. H2AC17 is a 14 kDa protein that is expressed in a variety of tissues, including blood cells, lymphoid organs, and solid organs. The H2AC17 protein is involved in the histone-coding process, which is the process by which the instructions in the DNA are translated into proteins.
H2AC17 has been shown to be involved in the regulation of cellular processes that are critical for the development and maintenance of cancer. For example, studies have shown that H2AC17 is involved in the regulation of cell growth, apoptosis (programmed cell death), and inflammation. H2AC17 has also been shown to play a role in the regulation of the immune response, which is an important aspect of cancer immune surveillance.
Due to its involvement in the regulation of cellular processes that are critical for the development and maintenance of cancer, H2AC17 has been identified as a potential drug target. Studies have shown that H2AC17 can be targeted by small molecules, such as inhibitors, which can inhibit the activity of H2AC17 and result in the inhibition of the processes that are critical for the development and maintenance of cancer.
In addition to its potential as a drug target, H2AC17 has also been shown to be a potential biomarker for the diagnosis and prognosis of cancer. Studies have shown that H2AC17 is expressed in a variety of tissues and that its levels can be used as a marker for the diagnosis and prognosis of cancer. For example, studies have shown that higher levels of H2AC17 are associated with poor prognosis in patients with diffuse large B-cell lymphoma, a type of cancer that affects the lymphatic system.
Overall, H2AC17 is a protein that is involved in the development and maintenance of cancer and has been identified as a potential drug target and biomarker. Further research is needed to fully understand the role of H2AC17 in the regulation of cellular processes and its potential as a therapeutic intervention.
Protein Name: H2A Clustered Histone 17
Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
The "H2AC17 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about H2AC17 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1 | H4C11 | H4C12 | H4C13 | H4C14 | H4C15 | H4C16 | H4C2 | H4C3 | H4C4 | H4C5 | H4C6 | H4C7 | H4C8 | H4C9 | H6PD | HAAO | HABP2 | HABP4 | HACD1 | HACD2 | HACD3 | HACD4 | HACE1 | HACL1 | HADH | HADHA | HADHAP1 | HADHB | HAFML | HAGH | HAGHL | HAGLR
