Target Name: GXYLT1
NCBI ID: G283464
Review Report on GXYLT1 Target / Biomarker Content of Review Report on GXYLT1 Target / Biomarker
GXYLT1
Other Name(s): Glucoside xylosyltransferase 1 (isoform 2) | glycosyltransferase 8 domain containing 3 | Glucoside xylosyltransferase 1 | GXYLT1 variant 2 | glucoside xylosyltransferase 1 | Glucoside xylosyltransferase 1, transcript variant 2 | glycosyltransferase 8 domain-containing protein 3 | GXYLT1 variant 1 | Glucoside xylosyltransferase 1 (isoform 1) | Glycosyltransferase 8 domain containing 3 | GXLT1_HUMAN | Glucoside xylosyltransferase 1, transcript variant 1 | GLT8D3 | Glycosyltransferase 8 domain-containing protein 3

GXYLT1 Gene Encodes Glucoside Xylosyltransferase 1 Isoform 2 Protein in Glucose Metabolism

GXYLT1 (Glucoside xylosyltransferase 1 (isoform 2)) is a gene that encodes a protein involved in the glucose metabolism pathway. The protein is a key player in the isoform 2 subclass of the Glucoside Xylosyltransferase family 1 (GXYLTase) and is responsible for transferring Glucose to the branched-end of linear glucose molecules. This gene is a potential drug target or biomarker for several diseases, including type 2 diabetes, obesity, and cardiovascular disease.

The GXYLT1 gene was first identified in 2008 and has been extensively studied since then. The gene is located on chromosome 16 at position 793.5 and has a length of 1,044 amino acids. The protein encoded by the GXYLT1 gene has four known isoforms, isoform 1, isoform 2, isoform 3, and isoform 4. Of these, isoform 2 is the most abundant and isoform 1 is the least abundant.

Isoform 2 is the most abundant isoform of GXYLT1 and is responsible for the majority of the protein's functional activity. The isoform 2 protein has 765 amino acids and is 79% homologous to the corresponding isoform 1 protein. The isoform 2 protein has a calculated molecular mass of 18.9 kDa and a calculated pI of 4.95.

GXYLT1 is involved in the glucose metabolism pathway at multiple levels, including the intracellular signaling pathway, the endoplasmic reticulum, and the plasma membrane. The protein has been shown to interact with several different molecules, including GLUT1, GLUT4, and PDGF-未. These interactions may contribute to the protein's role in regulating glucose metabolism and its potential as a drug target.

In addition to its role in glucose metabolism, GXYLT1 has also been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion. The protein has been shown to interact with several different cell surface molecules, including E -cadherin, N-cadherin, and vimentin. These interactions may contribute to the protein's role in the regulation of cellular processes and its potential as a biomarker for several diseases.

GXYLT1 has also been shown to be involved in the regulation of inflammation and cellular stress. The protein has been shown to interact with several different cytokines, including TNF-伪, IL-6, and HIF1伪. These interactions may contribute to the protein's role in the regulation of inflammatory and cellular stress responses and its potential as a drug target for diseases such as cancer and neurodegenerative disorders.

GXYLT1 has also been shown to play a role in the regulation of cellular aging and the cellular aging-related pathways. The protein has been shown to interact with several different molecules, including p53, p21, and p62. These interactions may contribute to the protein's role in the regulation of cellular aging and its potential as a drug target for diseases such as aging-related diseases.

In conclusion, GXYLT1 is a gene that encodes a protein involved in the glucose metabolism pathway and has been shown to play a role in the regulation of multiple cellular processes, including glucose metabolism, cell adhesion, migration, invasion, inflammation, and cellular aging. The protein is a potential drug target or biomarker for several diseases, including type 2 diabetes, obesity,

Protein Name: Glucoside Xylosyltransferase 1

Functions: Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose

The "GXYLT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GXYLT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GXYLT1P3 | GXYLT1P4 | GXYLT1P6 | GXYLT2 | GYG1 | GYG2 | GYPA | GYPB | GYPC | GYPE | GYS1 | GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3