H2B/t Protein: Key Regulator of H2 Receptor, Inflammation and Cellular Signaling
H2B/t Protein: Key Regulator of H2 Receptor, Inflammation and Cellular Signaling
H2BC20P, also known as H2B/t, is a protein that is expressed in high levels in the liver and other tissues. It is a key regulator of the H2 receptor, which is involved in the regulation of inflammation and cellular signaling.
The H2B/t protein is a member of the H2B family, which is known for its role in the regulation of various cellular processes, including inflammation, stress responses, and cell signaling. The H2B/t protein is a 20kDa transmembrane protein that is expressed in high levels in the liver, spleen, and other tissues.
One of the key functions of the H2B/t protein is its role in the regulation of the H2 receptor, which is a G protein-coupled receptor that is involved in the regulation of various cellular processes, including inflammation, stress responses, and cell signaling. The H2B/t protein is a key regulator of the H2 receptor, as it is able to interact with the receptor and regulate its activity.
In addition to its role in the regulation of the H2 receptor, the H2B/t protein is also involved in the regulation of inflammation and cellular signaling. It is a key regulator of the production of pro-inflammatory cytokines, such as TNF-alpha, IL-1, and IL-6. It is also involved in the regulation of the production of anti-inflammatory cytokines, such as IL-10.
The H2B/t protein is expressed in high levels in various tissues, including the liver, spleen, and lymphoid organs. It is typically expressed in the liver, where it is involved in the regulation of the production and degradation of various cytokines and enzymes involved in inflammation and cellular signaling.
In addition to its role in the regulation of cytokines and cellular signaling, the H2B/t protein is also involved in the regulation of inflammation. It is a key regulator of the production of pro-inflammatory cytokines, such as TNF-alpha, IL-1, and IL-6. It is also involved in the regulation of the production of anti-inflammatory cytokines, such as IL-10.
The H2B/t protein is also involved in the regulation of cellular signaling, including the regulation of cell proliferation and apoptosis. It is a key regulator of the production of cell cycle proteins, such as cyclin D1, and it is involved in the regulation of the apoptosis-associated protein Bcl-2.
In conclusion, the H2B/t protein is a key regulator of various cellular processes, including the regulation of the H2 receptor, inflammation, and cellular signaling. Its role in these processes makes it an attractive target for drug development, as potential therapeutic approaches may target the H2B/t protein in order to interfere with its activity. Further research is needed to fully understand the role of the H2B/t protein in these processes and to develop effective therapies that target this protein.
Protein Name: H2B Clustered Histone 20, Pseudogene
Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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More Common Targets
H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1 | H4C11 | H4C12 | H4C13 | H4C14 | H4C15 | H4C16 | H4C2 | H4C3 | H4C4 | H4C5 | H4C6 | H4C7 | H4C8 | H4C9 | H6PD | HAAO | HABP2 | HABP4 | HACD1 | HACD2 | HACD3 | HACD4 | HACE1 | HACL1 | HADH | HADHA | HADHAP1 | HADHB | HAFML | HAGH | HAGHL | HAGLR | HAGLROS | HAL | HAMP | HAND1 | HAND2 | HAND2-AS1 | HAO1 | HAO2 | HAO2-IT1 | HAP1 | HAPLN1 | HAPLN2 | HAPLN3 | HAPLN4 | HAPSTR1 | HAR1A | HAR1B | HARBI1 | HARS1 | HARS2 | HAS1 | HAS2 | HAS2-AS1 | HAS3 | HASPIN | HAT1 | HAUS1
