H2AC3P: A Protein Regulator of Hormonal Balance (G85303)
H2AC3P: A Protein Regulator of Hormonal Balance
H2AC3P, also known as H2A/T, is a protein that is expressed in the hypothalamus, which is the most important part of the brain that regulates various bodily functions. The hypothalamus is responsible for producing hormones that control a wide range of physiological processes, including temperature, hunger, thirst, and hormonal balance.
H2AC3P is a key regulator of these hormones, and is involved in the complex process of hypothalamus-pituitary-target organ axis regulation (HPA axis). The HPA axis is an important regulatory mechanism for the body to maintain homeostasis, which is achieved through the nervous system and endocrine system. H2AC3P plays a key role in the HPA axis, responsible for monitoring and regulating the regulatory effects of hormones secreted by the anterior pituitary gland on target organs.
H2AC3P is a protein composed of a single polypeptide chain, and its encoding gene is H2A/T. H2A is the first polypeptide chain of H2AC3P and consists of 114 amino acids. T is the conserved sequence number of H2AC3P, located at the N-terminus of the first polypeptide chain.
The function of H2AC3P is to regulate the physiological functions of target organs by binding to hormones secreted by the anterior pituitary gland. As a negatively charged cation, H2A can activate the ion channels of the target organ by binding to receptors on the target organ, thereby leading to ion flow and signal transmission, and regulating the physiological functions of the target organ. H2A can also bind to growth factors, thereby promoting cell proliferation and growth.
Abnormal expression of H2AC3P is closely related to the occurrence and development of various diseases. For example, in depression, abnormal expression of H2A/T may lead to neuronal apoptosis, leading to depressed mood and decreased cognitive function. In diabetes, abnormal expression of H2A/T may be related to insulin resistance and cell proliferation. In addition, abnormal expression of H2A/T is closely related to the occurrence and development of various tumors, such as breast cancer, lung cancer, and prostate cancer.
Therefore, H2AC3P is a very promising drug target. Studying the structure, function and drug target properties of H2A/T is of great significance for the treatment of various physiological and pathological diseases. With the continuous advancement of technology, H2AC3P, as a new drug target, is expected to bring more treatment options to the clinic.
Protein Name: H2A Clustered Histone 3, Pseudogene
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More Common Targets
H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1 | H4C11 | H4C12 | H4C13 | H4C14 | H4C15 | H4C16 | H4C2 | H4C3 | H4C4 | H4C5 | H4C6 | H4C7 | H4C8 | H4C9 | H6PD | HAAO | HABP2 | HABP4 | HACD1 | HACD2 | HACD3 | HACD4 | HACE1 | HACL1 | HADH | HADHA | HADHAP1 | HADHB | HAFML | HAGH | HAGHL | HAGLR | HAGLROS | HAL | HAMP | HAND1 | HAND2
