TXNDC11: A Potential Drug Target and Biomarker for Diseases (G51061)

Target Name: TXNDC11

NCBI ID: G51061

TXNDC11

TXNDC11: A Potential Drug Target and Biomarker for Diseases

TXNDC11 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of N-cadherin subfamily 11 (NC11) and is involved in several cellular processes, including cell adhesion , migration, and signaling. Despite its importance, little is known about TXNDC11 and its potential role in human disease. In this article, we will explore the biology of TXNDC11, its potential drug target status, and its potential as a biomarker for several diseases.

Biology of TXNDC11

TXNDC11 is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, and kidneys. It is a member of the superfamily of N-cadherin subfamily 11 (NC11) and is involved in several cellular processes, including cell adhesion, migration, and signaling.

One of the most significant functions of TXNDC11 is its role in cell adhesion. TXNDC11 is a critical protein for the formation of tight junctions, which are the junctions that connect adjacent cells and are involved in maintaining tissue structure and function. The primary form of connection involved in maintaining organizational structure and function. Under normal circumstances, tight junctions are formed by various protein interactions that keep cells tightly connected and prevent extracellular materials from penetrating into the cells. However, when cells are exposed to certain stimuli, tight junctions are altered, leading to an increase in the interstitial space and the penetration of extracellular materials into the cells. Therefore, studying the role of TXNDC11 in cell adhesion is of great significance for understanding the pathogenesis of many diseases.

In addition, TXNDC11 is also involved in cell migration and differentiation. Under normal circumstances, cells need to migrate and differentiate to adapt to changing environments. TXNDC11 plays an important role in cell migration and differentiation. Studies have shown that the loss of TXNDC11 can lead to abnormal cell migration and differentiation. Therefore, TXNDC11 can serve as a potential drug target for the treatment of many tumors and other diseases.

Potential drug target status

As a protein, TXNDC11 has an important potential to become a drug target. Its function is closely related to the pathogenesis of many diseases, therefore, the inhibition or activation of TXNDC11 can have an impact on many diseases.

First, TXNDC11 is a potential tumor target. Many tumor cells express TXNDC11, therefore, inhibition of TXNDC11 can inhibit the growth and spread of tumor cells. Studies have shown that inhibition of TXNDC11 can significantly inhibit the growth of a variety of tumors, including breast cancer, lung cancer, and prostate cancer. Therefore, TXNDC11 can be used as a potential tumor target for the treatment of various tumors.

Secondly, TXNDC11 is also a potential neuroscience target. TXNDC11 plays an important role in neuronal cell adhesion and synapse formation between neurons. Studies have shown that activation of TXNDC11 can increase synapse formation between neurons, while inhibition of TXNDC11 can reduce synapse formation between neurons. Therefore, TXNDC11 can be used as a potential neuroscience target for the treatment of neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease, etc.

Finally, TXNDC11 is also a potential immune system target. TXNDC11 plays an important role in immune cell recognition and immune cell activation. Studies have shown that activation of TXNDC11 can enhance the activity and cytotoxicity of immune cells, while inhibition of TXNDC11 can inhibit the activity and cytotoxicity of immune cells. Therefore, TXNDC11 can serve as a potential immune system target for the treatment of autoimmune diseases, such as

Protein Name: Thioredoxin Domain Containing 11

Functions: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation

The "TXNDC11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TXNDC11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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