Target Name: TXLNG
NCBI ID: G55787
Review Report on TXLNG Target / Biomarker Content of Review Report on TXLNG Target / Biomarker
TXLNG
Other Name(s): TXLNG variant 1 | lipopolysaccharide specific response-5 protein | TXLNG_HUMAN | Factor inhibiting ATF4-mediated transcription | environmental LPS-responding | environmental lipopolysaccharide-responding gene protein | Gamma-taxilin (isoform 1) | Environmental lipopolysaccharide-responding gene protein | TXLNGX | factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription | Lipopolysaccharide-specific response protein 5 | FIAT | LSR5 | factor inhibiting ATF4-mediated transcription | lipopolysaccharide-specific response protein 5 | Taxilin gamma, transcript variant 1 | CXorf15 | gamma-taxilin | Gamma-taxilin | ELRG | taxilin gamma

TXLNG: A Potential Therapeutic Target for Alzheimer's Disease

TXLNG (TXLNG variant 1) is a protein that is expressed in the brain and is known for its role in the regulation of cell death. It has been shown to play a crucial role in the development and progression of various neurological disorders, including Alzheimer's disease.

TXLNG is a member of the superfamily of cysteine-rich proteins, known as the TXLNG family. This family of proteins is characterized by the presence of a specific cysteine residue, which is important for their structural stability and function.

The TXLNG protein is synthesized in the brain and has been shown to be involved in the regulation of cell death, particularly in the context of neurodegenerative diseases. It is well established that neurodegenerative diseases, such as Alzheimer's disease, are characterized by the progressive loss of brain cells, which is thought to be caused by a combination of genetic and environmental factors.

One of the key factors that have been identified in the regulation of cell death is the role of TXLNG. Studies have shown that TXLNG plays a crucial role in the regulation of neurodegenerative diseases, including Alzheimer's disease.

For example, studies have shown that individuals with the genetic mutation associated with Alzheimer's disease have lower levels of TXLNG in their brains compared to individuals without the mutation. This suggests that the regulation of cell death by TXLNG may be a potential therapeutic target for the treatment of Alzheimer's disease.

In addition to its role in the regulation of cell death, TXLNG has also been shown to play a role in the regulation of neurotransmitter release and the modulation of pain perception. This suggests that it may be a potential drug target for the treatment of a wide range of neurological disorders.

TXLNG is also a good candidate as a biomarker for diagnostic purposes in neurodegenerative diseases, as its levels can be easily measured and its effects on cell death can be detected in a timely manner. This suggests that it may be a valuable tool for the diagnosis and prognosis of neurodegenerative diseases.

In conclusion, TXLNG (TXLNG variant 1) is a protein that is expressed in the brain and is known for its role in the regulation of cell death. Its role in the regulation of neurodegenerative diseases, including Alzheimer's disease, makes it a potential therapeutic target for the treatment of these disorders. Furthermore, its potential as a biomarker for diagnostic purposes in neurodegenerative diseases makes it an attractive candidate for further research.

Protein Name: Taxilin Gamma

Functions: May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression

The "TXLNG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TXLNG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TXLNGY | TXN | TXN2 | TXNDC11 | TXNDC12 | TXNDC15 | TXNDC16 | TXNDC17 | TXNDC2 | TXNDC5 | TXNDC8 | TXNDC9 | TXNIP | TXNL1 | TXNL1P1 | TXNL4A | TXNL4B | TXNP6 | TXNRD1 | TXNRD2 | TXNRD3 | TXNRD3NB | TYK2 | TYMP | TYMS | TYMSOS | Type II Transmembrane serine protease | TYR | TYRO3 | TYRO3P | TYROBP | Tyrosine Kinase | Tyrosine-Protein Kinase ABL | Tyrosine-Protein Kinases Src | Tyrosyl-DNA phosphodiesterase TDP | TYRP1 | TYSND1 | TYW1 | TYW1B | TYW3 | U2 small nuclear ribonucleoprotein auxiliary factor | U2AF1 | U2AF1L4 | U2AF2 | U2SURP | U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex | U5 small nuclear ribonucleoprotein complex | U7 snRNP complex | UACA | UAP1 | UAP1L1 | UBA1 | UBA2 | UBA3 | UBA5 | UBA52 | UBA52P1 | UBA6 | UBA6-DT | UBA7 | UBAC1 | UBAC2 | UBAC2-AS1 | UBALD1 | UBALD2 | UBAP1 | UBAP1L | UBAP2 | UBAP2L | UBASH3A | UBASH3B | UBB | UBBP1 | UBBP2 | UBBP4 | UBC | UBD | UBDP1 | UBE2A | UBE2B | UBE2C | UBE2CP3 | UBE2CP4 | UBE2D1 | UBE2D2 | UBE2D3 | UBE2D3P1 | UBE2D4 | UBE2DNL | UBE2E1 | UBE2E2 | UBE2E3 | UBE2F | UBE2F-SCLY | UBE2FP1 | UBE2G1 | UBE2G2 | UBE2H | UBE2HP1 | UBE2I