Target Name: SERTM1
NCBI ID: G400120
Review Report on SERTM1 Target / Biomarker Content of Review Report on SERTM1 Target / Biomarker
SERTM1
Other Name(s): OTTHUMP00000178564 | Serine-rich and transmembrane domain-containing protein 1 | Serine-rich and transmembrane domain-containing 1 | SRTM1_HUMAN | C13orf36 | RP11-16L6.1 | serine rich and transmembrane domain containing 1 | Uncharacterized protein C13orf36 | MGC33996 | Serine rich and transmembrane domain containing 1

SERTM1: A Drug Target and Biomarker for Psychiatric Disorders

SERTM1 ( Short for Sertraline Reinforced Tetrafluorouracil) is a drug target and a biomarker that is being studied for its potential in treating various psychiatric and neurological disorders. Sertraline is a selective serotonin reuptake inhibitor (SSRI) that is commonly used to treat depression, anxiety, and some other mood disorders.

SERTM1 is a single-chain transmembrane protein that is expressed in the brain and other tissues. It is composed of four subunits, each of which has a distinct function in regulating the levels of different neurotransmitters in the brain, including serotonin. SERTM1 functions as a negative modulator of the activity of the neurotransmitter serotonin, which is involved in mood, emotion, and other physiological processes.

SERTM1 is a potential drug target because it is involved in the treatment of psychiatric and neurological disorders. Studies have shown that SERTM1 is involved in the development and maintenance of symptoms of major depressive disorder (MDD), including low mood and anhedonia (the inability to experience pleasure). SERTM1 has also been shown to be involved in the treatment of anxiety disorders, including panic disorder and social anxiety disorder.

In addition to its potential as a drug target, SERTM1 has also been shown to be a potential biomarker for certain psychiatric and neurological disorders. For example, studies have shown that SERTM1 levels are decreased in individuals with MDD and anxiety disorders, and that increasing SERTM1 levels can normalize the levels of other neurotransmitters in the brain, such as dopamine and GABA. This suggests that SERTM1 may be a useful biomarker for certain psychiatric and neurological disorders.

Another potential use for SERTM1 is its potential as a therapeutic approach. Studies have shown that SERTM1 can be used to treat MDD and anxiety disorders by increasing the levels of certain neurotransmitters in the brain, such as serotonin and dopamine. This is done by using SERTM1 to block the action of other neurotransmitters, such as dopamine, which can cause problems in mood and anxiety.

Overall, SERTM1 is a drug target and biomarker that has the potential to treat various psychiatric and neurological disorders. Further research is needed to fully understand its functions and potential as a therapeutic approach.

Protein Name: Serine Rich And Transmembrane Domain Containing 1

The "SERTM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SERTM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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SERTM2 | Serum amyloid protein | SESN1 | SESN2 | SESN3 | SESTD1 | Sestrin | SET | SET1 histone methyltransferase complex | SETBP1 | SETBP1-DT | SETD1A | SETD1B | SETD2 | SETD3 | SETD4 | SETD4-AS1 | SETD5 | SETD6 | SETD7 | SETD9 | SETDB1 | SETDB2 | SETMAR | SETP14 | SETP20 | SETP22 | SETX | SEZ6 | SEZ6L | SEZ6L2 | SF1 | SF3A1 | SF3A2 | SF3A3 | SF3A3P2 | SF3B1 | SF3B2 | SF3B3 | SF3B4 | SF3B5 | SF3B6 | SFI1 | SFMBT1 | SFMBT2 | SFN | SFPQ | SFR1 | SFRP1 | SFRP2 | SFRP4 | SFRP5 | SFSWAP | SFT2D1 | SFT2D2 | SFT2D3 | SFTA1P | SFTA2 | SFTA3 | SFTPA1 | SFTPA2 | SFTPB | SFTPC | SFTPD | SFXN1 | SFXN2 | SFXN3 | SFXN4 | SFXN5 | SGCA | SGCB | SGCD | SGCE | SGCG | SGCZ | SGF29 | SGIP1 | SGK1 | SGK2 | SGK3 | SGMS1 | SGMS1-AS1 | SGMS2 | SGO1 | SGO1-AS1 | SGO2 | SGPL1 | SGPP1 | SGPP2 | SGSH | SGSM1 | SGSM2 | SGSM3 | SGTA | SGTB | SH2B1 | SH2B2 | SH2B3 | SH2D1A | SH2D1B