SGPL1 Plays A Role in Cell Signaling, Adhesion and Stress Response

Target Name: SGPL1

NCBI ID: G8879

SGPL1

SGPL1 Plays A Role in Cell Signaling, Adhesion and Stress Response

SGPL1 (SGPL1_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the SGPL1 family, which is characterized by the presence of a unique domain called N-terminal alpha helix. SGPL1 is highly conserved across various species, and it has been implicated in various cellular processes, including cell adhesion, migration, and invasion.

One of the unique aspects of SGPL1 is its ability to form a complex with other proteins, including the protein tyrosine phosphatase (PTP). This interaction between SGPL1 and PTP has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and metabolism.

SGPL1 is also known to interact with the protein Fyn, which is involved in the intracellular signaling pathway known as the T cell receptor (TCR) signaling pathway. This interaction between SGPL1 and Fyn has been shown to regulate the activity of TCR signaling, and it is thought to contribute to the regulation of cellular immune responses.

Another interesting property of SGPL1 is its ability to form a complex with the protein Myb, which is involved in the development and maintenance of neural networks. This interaction between SGPL1 and Myb has been shown to play a role in the regulation of neural network function, and it is thought to contribute to the development of various neurological disorders.

In addition to its role in cellular signaling, SGPL1 is also known to be involved in the regulation of various cellular processes, including cell division, DNA replication, and metabolism. It is a component of the machinery that ensures the faithful transmission of genetic information from one generation to the next, and it plays a critical role in the regulation of DNA replication, which is essential for the growth and development of all living organisms.

SGPL1 is also involved in the regulation of cellular adhesion, which is the process by which cells stick together to form tissues and organs. This interaction between SGPL1 and adhesion molecules is thought to contribute to the regulation of tissue repair and regeneration, and it is a potential therapeutic target for various diseases, including cancer.

In addition to its role in cellular signaling and adhesion, SGPL1 is also involved in the regulation of various cellular processes that are critical for the survival and survival of cells. This interaction between SGPL1 and cellular stress response pathways is thought to contribute to the regulation of cellular stress resistance, and it is a potential therapeutic target for various diseases, including neurodegenerative disorders.

SGPL1 is also involved in the regulation of cellular immigration, which is the process by which cells move from the cell body to the plasma membrane. This interaction between SGPL1 and the cadherin protein is thought to contribute to the regulation of cell migration, and it is a potential therapeutic target for various diseases, including cancer.

In addition to its role in cellular signaling and immigration, SGPL1 is also involved in the regulation of various cellular processes that are critical for the survival and survival of cells. This interaction between SGPL1 and the protein p53 is thought to contribute to the regulation of cellular apoptosis, which is the process by which cells die as a result of various cellular stressors.

SGPL1 is also involved in the regulation of cellular inflammation, which is the process by which the body responds to the presence of foreign substances in the body. This interaction between SGPL1 and various signaling pathways, including the production of inflammatory cytokines, is thought to contribute to the regulation of cellular inflammation, and it is a potential therapeutic target for various diseases, including autoimmune disorders.

In conclusion, SGPL1 is a protein that is involved in various cellular processes that are critical for the survival and survival of cells. Its unique ability to form a complex with other proteins, including the protein tyrosine phosphatase (PTP

Protein Name: Sphingosine-1-phosphate Lyase 1

Functions: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity). Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity)

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•   general information;
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•   expression level;
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