SGSH: A Protein Involved in Cell Signaling, Apoptosis and Cellular Processes

Target Name: SGSH

NCBI ID: G6448

SGSH

SGSH: A Protein Involved in Cell Signaling, Apoptosis and Cellular Processes

SGSH (sulphamidase) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and muscle. It is a member of the superfamily of proteins known as signal transduction enzymes, which are involved in the regulation of cellular signaling pathways.

One of the key functions of SGSH is its role in the regulation of cell signaling pathways. SGSH is a potent inhibitor of the protein tyrosine phosphatase, which is a key enzyme involved in the regulation of many signaling pathways in the cell. This means that when SGSH is present in a cell, it can prevent tyrosine phosphatase from breaking down tyrosine, which can lead to the activation of signaling pathways and the regulation of cellular processes.

SGSH has also been shown to play a role in the regulation of cellular apoptosis, which is the process by which cells die when they have reached a certain level of stress or damage. SGSH has also been shown to induce apoptosis in a variety of cell types, including cancer cells, and to play a role in the regulation of cell cycle progression.

In addition to its role in cell signaling and apoptosis, SGSH has also been shown to have a variety of other functions in the cell. For example, it has been shown to play a role in the regulation of cell adhesion, which is the process by which cells stick together and form tissues. SGSH has also been shown to play a role in the regulation of cell migration, which is the process by which cells move from one location to another in the body.

Given its diverse range of functions and its involvement in the regulation of many cellular processes, SGSH has been identified as a potential drug target. Many studies have suggested that SGSH may be a useful target for the development of new pharmaceuticals for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the challenges in the development of SGSH as a drug target is its complex structure and the difficulty of studying its function in living organisms. However, researchers are making progress in understanding its mechanisms of action and are developing new techniques for its study, such as live cell imaging, biochemical assays, and mass spectrometry.

In addition to its potential use as a drug target, SGSH has also been shown to have a potential as a biomarker for a variety of diseases. For example, it has been shown to be elevated in the blood of individuals with certain types of cancer, and to be decreased in the blood of individuals with certain types of neurodegenerative diseases. These findings suggest that SGSH may be a useful biomarker for the diagnosis and treatment of these diseases.

Overall, SGSH is a protein that has a diverse range of functions in the cell, and its potential as a drug target and biomarker make it an attractive target for further research. Further studies are needed to fully understand its mechanisms of action and its potential as a therapeutic agent.

Protein Name: N-sulfoglucosamine Sulfohydrolase

Functions: Catalyzes a step in lysosomal heparan sulfate degradation

The "SGSH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SGSH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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