Target Name: SGK2
NCBI ID: G10110
Review Report on SGK2 Target / Biomarker Content of Review Report on SGK2 Target / Biomarker
SGK2
Other Name(s): serum/glucocorticoid regulated kinase 2 | Serum/glucocorticoid regulated kinase 2 (isoform beta) | dJ138B7.2 | H-SGK2 | SGK2_HUMAN | SGK2, serine/threonine kinase 2 | Serine/threonine-protein kinase Sgk2 | Serum/glucocorticoid regulated kinase 2, transcript variant 2 | Serum/glucocorticoid-regulated kinase 2 | SGK2 variant 2

SGK2: A Drug Target / Disease Biomarker

SGK2 (Sodium channels interacting with G protein-coupled receptors 2) is a protein that is expressed in many different tissues throughout the body. It is a key regulator of neural and cardiac function and is involved in a wide range of physiological processes, including muscle contractions and ion channels. SGK2 has also been shown to play a key role in the development and progression of several diseases, including cancer. As a result, SGK2 has become a focus of interest for researchers and pharmaceutical companies looking for new treatments.

SGK2 is a transmembrane protein that is composed of four distinct subunits. The first subunit consists of a catalytic alpha-helices that is responsible for the formation of the protein. The second subunit consists of a transmembrane region that is involved in the regulation of ion channels. The third subunit consists of a carboxy-terminal region that is responsible for the interaction of SGK2 with its ligands. The fourth subunit is a C-terminal region that is responsible for the stability and localization of the protein.

SGK2 is a protein that is expressed in many different tissues throughout the body, including the brain, heart, and muscles. It is also expressed in the placenta, which is responsible for providing nutrients and oxygen to the developing fetus. SGK2 is thought to play a key role in the regulation of neural and cardiac function, as well as ion channels and pain perception.

One of the most promising aspects of SGK2 is its potential as a drug target. Several studies have shown that SGK2 is involved in a wide range of physiological processes, including the regulation of muscle contractions, the development of cancer, and the regulation of pain perception. As a result, SGK2 has become a focus of interest for researchers and pharmaceutical companies looking for new treatments.

One of the key challenges in studying SGK2 is its complex structure. SGK2 is a protein that is composed of four distinct subunits that are involved in the regulation of many different physiological processes. It is also a protein that is prone to undergo conformational changes, which can affect its function. As a result, studying SGK2 is a complex and challenging task that requires a combination of biochemical, cellular, and computational techniques.

In addition to its potential as a drug target, SGK2 is also of interest to researchers because of its involvement in the regulation of many different physiological processes. For example, SGK2 is involved in the regulation of muscle contractions, which are essential for movement and maintaining posture. It is also involved in the regulation of ion channels, which are responsible for the flow of electrical signals through cells. SGK2 is also involved in the regulation of pain perception, which is important for the maintenance of tissue homeostasis and the development of pain sensitivity.

SGK2 has also been shown to play a key role in the development and progression of several diseases, including cancer. For example, studies have shown that SGK2 is involved in the regulation of cell division and the development of cancer cells. It is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. As a result, SGK2 has become a focus of interest for researchers and pharmaceutical companies looking for new treatments for cancer.

In conclusion, SGK2 is a protein that is expressed in many different tissues throughout the body and is involved in a wide range of physiological processes. It is also a key regulator of neural and cardiac function and has been shown to play a key role in the development and progression of several diseases, including cancer. As a result, SGK2 has become a focus of interest for researchers and pharmaceutical companies looking for new treatments. Further research is needed to fully understand the functions of SGK2 and its potential as a drug target.

Protein Name: Serum/glucocorticoid Regulated Kinase 2

Functions: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase

The "SGK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SGK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SGK3 | SGMS1 | SGMS1-AS1 | SGMS2 | SGO1 | SGO1-AS1 | SGO2 | SGPL1 | SGPP1 | SGPP2 | SGSH | SGSM1 | SGSM2 | SGSM3 | SGTA | SGTB | SH2B1 | SH2B2 | SH2B3 | SH2D1A | SH2D1B | SH2D2A | SH2D3A | SH2D3C | SH2D4A | SH2D4B | SH2D5 | SH2D6 | SH2D7 | SH3 domain-binding protein 1 | SH3BGR | SH3BGRL | SH3BGRL2 | SH3BGRL3 | SH3BP1 | SH3BP2 | SH3BP4 | SH3BP5 | SH3BP5-AS1 | SH3BP5L | SH3D19 | SH3D21 | SH3GL1 | SH3GL1P1 | SH3GL1P2 | SH3GL1P3 | SH3GL2 | SH3GL3 | SH3GLB1 | SH3GLB2 | SH3KBP1 | SH3PXD2A | SH3PXD2A-AS1 | SH3PXD2B | SH3RF1 | SH3RF2 | SH3RF3 | SH3RF3-AS1 | SH3TC1 | SH3TC2 | SH3TC2-DT | SH3YL1 | SHANK1 | SHANK2 | SHANK2-AS1 | SHANK2-AS3 | SHANK3 | SHARPIN | SHB | SHBG | SHC1 | SHC2 | SHC3 | SHC4 | SHCBP1 | SHCBP1L | SHD | SHE | SHF | SHFL | SHH | SHISA2 | SHISA3 | SHISA4 | SHISA5 | SHISA6 | SHISA7 | SHISA8 | SHISA9 | SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2