SFRP2: A Potential Drug Target and Biomarker (G6423)

Target Name: SFRP2

NCBI ID: G6423

SFRP2

SFRP2: A Potential Drug Target and Biomarker

Sfrp2, a protein that belongs to the Src tyrosine kinase family, is expressed in various tissues and cell types throughout the body. Its primary function is to regulate cell proliferation and survival, and it is considered a key regulator of cell-cell adhesion. Sfrp2 has been implicated in the development and progression of many diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. As a result, targeting Sfrp2 has become an attractive research topic in recent years.

Drug Target Potential

Sfrp2 has been identified as a potential drug target due to its involvement in several cellular processes that are associated with disease progression. Sfrp2 has been shown to play a role in the regulation of cell cycle progression, apoptosis, angiogenesis, and inflammation. It has also been implicated in the regulation of T cell development and function. Therefore, targeting Sfrp2 with drugs that can modulate its activity could be an effective way to treat various diseases.

Biomarker Potential

Sfrp2 has also been identified as a potential biomarker for several diseases. Its expression has been shown to be elevated in several types of cancer, including breast, ovarian, and prostate cancer. Additionally, Sfrp2 has been shown to be involved in the regulation of cell-cell adhesion, which is a critical process in the development of cancer. Therefore, measuring the expression of Sfrp2 could be an effective way to monitor the effectiveness of anti-cancer treatments.

Expression and Localization

Sfrp2 is a protein that is expressed in a variety of tissues and cell types throughout the body. It is mainly expressed in the brain, pancreas, and gastrointestinal tract, and it is also expressed in the heart, blood vessels, and other organs. Sfrp2 is involved in the regulation of cell proliferation and survival, and it has been shown to localize to the plasma membrane of cells.

Function and Interaction

Sfrp2 is involved in the regulation of several cellular processes that are essential for cell survival. It has been shown to play a role in the regulation of cell cycle progression, apoptosis, and angiogenesis. Sfrp2 has also been shown to regulate the migration and invasion of cancer cells. Additionally, Sfrp2 has been shown to play a role in the regulation of T cell development and function.

Sfrp2 has also been shown to interact with several other proteins, including T cell receptor 伪, 尾, and 纬. These interactions are critical for the regulation of T cell function and their regulation of cellular processes. Sfrp2 has also been shown to interact with the protein FAK, which is involved in cell adhesion, migration, and invasion.

Conclusion

Sfrp2 is a protein that has been shown to play a role in the regulation of multiple cellular processes that are associated with disease progression. Its potential as a drug target and biomarker makes it an attractive topic for further research. Further studies are needed to determine the exact mechanism of Sfrp2's role in disease progression and to develop effective treatments that can modulate its activity.

Protein Name: Secreted Frizzled Related Protein 2

Functions: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis

The "SFRP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SFRP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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