SGPP2: Key Regulator of Cell Signaling and Gene Expression (G130367)

Target Name: SGPP2

NCBI ID: G130367

SGPP2

SGPP2: Key Regulator of Cell Signaling and Gene Expression

SGPP2 (hSPP2) is a protein that is expressed in many tissues throughout the body. It is a key regulator of cell signaling, and is involved in the development and maintenance of tissues such as hair, nails, and bones. SGPP2 has also been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, SGPP2 has generated a lot of interest as a potential drug target or biomarker.

One of the key features of SGPP2 is its role in cell signaling. SGPP2 is a key regulator of the Smad/TAZ signaling pathway, which is involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. This pathway is important for the development and maintenance of tissues, and SGPP2 plays a key role in ensuring that cells are able to respond properly to changes in their environment.

In addition to its role in cell signaling, SGPP2 is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of the expression of genes involved in cell adhesion, migration, and survival. This suggests that SGPP2 may be involved in the development and maintenance of tissues that are able to respond to changes in their environment, such as the skin and the nervous system.

SGPP2 has also been shown to be involved in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that SGPP2 is involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. This suggests that SGPP2 may be a useful target for drugs that are designed to treat these conditions.

In addition to its potential as a drug target, SGPP2 has also generated a lot of interest as a biomarker. This is because it is often expressed in a variety of tissues and can be easily isolated and purified. This makes it possible to study the effects of drugs on SGPP2 expression and to use it as a tool for the diagnosis and treatment of diseases.

Overall, SGPP2 is a protein that is involved in a variety of processes in the body. Its role in cell signaling and gene expression makes it a potential target for drugs, and its involvement in the development and maintenance of tissues makes it a valuable biomarker. Further research is needed to fully understand the effects of SGPP2 on human health and to develop treatments that can effectively target it.

Protein Name: Sphingosine-1-phosphate Phosphatase 2

Functions: Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (PubMed:12411432). Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (By similarity). May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling (PubMed:17113265). Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation (By similarity)

The "SGPP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SGPP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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