SM-A1: A Potent Insecticide and Potential Drug Target (G94081)

Target Name: SFXN1

NCBI ID: G94081

SFXN1

SM-A1: A Potent Insecticide and Potential Drug Target

SFXN1 (SLC56A1) is a gene that encodes a protein known as sphingomyelinase A1 (SM-A1). SM-A1 is a potent insecticidal toxin that is found in the venom of the Loxosceles spider, which is commonly found in soil, grass, and other plants.

SM-A1 is a member of the superfamily of cysteine 鈥嬧?媝roteases, which are a group of enzymes that carry out a variety of functions in the cell. These enzymes are characterized by the presence of a characteristic Rossmann-fold, which is a structural motif that is found in the active site of the enzyme.

SM-A1 is unique in that it is a potent insecticide that is specific to the Loxosceles spider. This spider is known to cause significant damage to crops, including agricultural fields, apple trees, and greenhouse plants. SM-A1 has been shown to be Effective in killing a variety of spider species, including Loxosceles spider, which is the most dangerous spider in the world.

The potential use of SFXN1 as a drug target or biomarker is due to its unique properties, including its ability to specifically target the Loxosceles spider and its high potency as an insecticide.

SM-A1 can be used as a drug target due to its unique structure and its ability to interact with specific molecules. One of the most promising aspects of SFXN1 as a drug target is its ability to interact with the protein FERMT1. FERMT1 is a protein that is involved in the regulation of cell division and is a potential target for SM-A1.

Research has shown that SM-A1 can inhibit the activity of FERMT1, which could lead to the inhibition of cell division and the potential for the treatment of various diseases. Additionally, SFXN1 has been shown to interact with the protein casein, which is a protein found in the cell membrane that is involved in the regulation of intracellular signaling. This interaction between SFXN1 and casein could potentially lead to the inhibition of intracellular signaling and the potential for the treatment of various diseases.

SM-A1 can also be used as a biomarker due to its unique properties, including its ability to specifically target the Loxosceles spider and its high potency as an insecticide. The Loxosceles spider is known to cause significant damage to crops, including agricultural fields, apple trees, and greenhouse plants. SM-A1 has been shown to be effective in killing a variety of spider species, including Loxosceles spider, which is the most dangerous spider in the world.

The potential use of SFXN1 as a drug target or biomarker is still in its early stages, but it holds great promise due to its unique properties and its ability to interact with specific molecules. Further research is needed to fully understand the potential uses of SFXN1 as a drug target or biomarker.

Protein Name: Sideroflexin 1

Functions: Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). May also transport other amino acids including alanine and cysteine (PubMed:30442778)

The "SFXN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SFXN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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