Target Name: MIR140
NCBI ID: G406932
Review Report on MIR140 Target / Biomarker Content of Review Report on MIR140 Target / Biomarker
MIR140
Other Name(s): hsa-miR-140-5p | MIRN140 | miRNA140 | SEDN | hsa-mir-140 | microRNA 140 | MicroRNA 140 | mir-140 | hsa-miR-140-3p

MIR140: A Non-Coding RNA Molecule as A Potential Drug Target Or Biomarker

MIR140 (hsa-miR-140-5p) is a non-coding RNA molecule that has been identified as a potential drug target or biomarker in various diseases, including cancer. Its unique structure and expression patterns have made it an attractive target for researchers to study, and various studies have shown its potential in different fields, such as drug discovery, diagnostics, and gene regulation.

MIR140 is a microRNA (miRNA) molecule that is expressed in various tissues and cells throughout the body. It is a part of the miRNA-140 family, which consists of 18 known miRNA molecules. These molecules are known to target specific mRNAs for degradation, and MIR140 is no exception. It is designed to target and reduce the expression of specific target mRNAs, which can lead to the inhibition of gene expression and the development of various diseases.

One of the most significant aspects of MIR140 is its expression patterns. It is expressed in various tissues, including the brain, heart, liver, and muscle, and its levels vary depending on the cell type and the developmental stage of the organism. This allows researchers to study the role of MIR140 in different biological processes and to identify potential drug targets in different tissues.

MIR140 has also been shown to play a role in cancer development. Several studies have shown that MIR140 is aberrantly expressed in various types of cancer, including breast, ovarian, and prostate cancer. It is also associated with cancer stem cells, which are a common subset of cancer cells that have the ability to self-renew and promote tumor growth. Therefore, targeting MIR140 has been shown to be an effective way to inhibit cancer stem cell growth and to treat various types of cancer.

Another potential application of MIR140 is its use as a biomarker. Its aberrant expression patterns make it an attractive target for diagnostic tests, such as qRT-PCR, microarray, and Western hybridization. These tests can be used to detect and measure the levels of MIR140 in different tissues and cells, which can provide valuable information about the status of a disease or the effectiveness of a drug.

In addition to its potential as a drug target or biomarker, MIR140 is also of interest due to its unique structure. It is a small molecule that consists of only 19 amino acid residues and has a calculated molecular weight of 20.4 kDa. This small size and the presence of a conserved cysteine 鈥嬧?媟esidue at its side make it a stable molecule that is relatively easy to synthesize and manipulate.

Several studies have shown that MIR140 can be targeted to the endoplasmic reticulum (ER) and can interact with various drug-protein interactions, including those between drug and protein targets. This interaction suggests that MIR140 may be a useful drug target in the future. Furthermore , the conserved cysteine 鈥嬧?媟esidue at its side also suggests that it may be a good candidate for small molecule inhibitors.

In conclusion, MIR140 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker in various diseases. Its unique structure and expression patterns make it an attractive target for researchers to study, and various studies have shown its potential in different fields. Further research is needed to fully understand the role of MIR140 in different biological processes and to develop effective drugs and diagnostics based on it.

Protein Name: MicroRNA 140

The "MIR140 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR140 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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