MYO9A: A Potential Drug Target and Biomarker for Muscle-Related Conditions

Target Name: MYO9A

NCBI ID: G4649

MYO9A

MYO9A: A Potential Drug Target and Biomarker for Muscle-Related Conditions

Myosin-IXa (MYO9A) is a protein that plays a critical role in muscle contraction and relaxation. It is a key component of the myosin filament, which is the protein that powers muscle growth and development. MYO9A is a 21-kDa protein that is expressed in muscle fibers, and it is responsible for the rapid and forceful contractions that occur during muscle activity.

MYO9A is a protein that has been identified as a potential drug target for a variety of muscle-related conditions, including muscle dystrophy, muscle weakness, and muscle overuse. It is also a potential biomarker for muscle damage and repair. In this article, we will explore the role of MYO9A in muscle physiology and discuss its potential as a drug target and biomarker.

The Importance of Myosin-IXa

Myosin-IXa is a key component of muscle contraction and relaxation. It is responsible for the rapid and forceful contractions that occur during muscle activity. When muscle fibers contract, the myosin filament binds to the actin protein and pulls it together, creating a micro-fibril. This micro-fibril then bonds to the myosin ATPase, which allows the muscle fibers to store energy and begin the contraction process. Once the muscle fibers have contracted, the myosin filament releases from the actin protein, allowing the muscle fibers to relax and prepare for the next contraction.

MYO9A is a 21-kDa protein that is expressed in muscle fibers and is responsible for the rapid and forceful contractions that occur during muscle activity. It is a key component of the myosin filament and plays a critical role in muscle physiology.

MYO9A as a Drug Target

MYO9A has been identified as a potential drug target for a variety of muscle-related conditions, including muscle dystrophy, muscle weakness, and muscle overuse. One of the reasons for its potential as a drug target is its location on the molecular map.MYO9A is located in the center of the myosin filament, which makes it a target that is difficult to reach with small molecules. Additionally,MYO9A has a high degree of cross-reactivity with several other myosin proteins, which makes it a more attractive target than some other proteins.

MYO9A has also been shown to play a role in several muscle-related conditions. For example, studies have shown thatMYO9A levels are decreased in muscle fibers that are affected by muscle dystrophy, and that it is a potential therapeutic target for this condition. Additionally,MYO9A has been shown to be involved in muscle weakness and muscle overuse, and may be a potential biomarker for these conditions.

MYO9A as a Biomarker

MYO9A is also a potential biomarker for muscle damage and repair. It is expressed in muscle fibers and has been shown to be involved in the repair process after muscle damage. Additionally,MYO9A has been shown to be involved in the regulation of muscle growth and development, and may be a potential target for drugs that are used to promote muscle growth and development.

Conclusion

MYO9A is a protein that plays a critical role in muscle physiology and has been identified as a potential drug target for a variety of muscle-related conditions. It is located in the center of the myosin filament, making it a target that is difficult to reach with small molecules, and has a high degree of cross-reactivity with several other myosin proteins. Additionally,MYO9A has been shown to play a role in several muscle-related conditions, including muscle dystrophy, muscle weakness, and muscle overuse, and may be a potential biomarker for these conditions. Further research is needed to fully understand the role of MYO9A in muscle physiology and to determine its potential as a drug target and biomarker.

Protein Name: Myosin IXA

Functions: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity)

The "MYO9A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYO9A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets