Target Name: MYORG
NCBI ID: G57462
Review Report on MYORG Target / Biomarker Content of Review Report on MYORG Target / Biomarker
MYORG
Other Name(s): Uncharacterized family 31 glucosidase KIAA1161 | myogenesis regulating glycosidase (putative) | IBGC7 | Myogenesis regulating glycosidase (putative) | KIAA1161 | NET37 | Myogenesis-regulating glycosidase | MYORG_HUMAN

MYORG: A Critical Enzyme for Proper Body Function

Myorg (Uncharacterized family 31 glucosidase KIAA1161) is a protein that is expressed in various tissues throughout the body, including the liver, pancreas, and muscle. It is a member of the family of enzymes known as glucosidases, which are responsible for breaking down the sugar molecules that make up carbohydrates.

MYORG is expressed in humans at different levels, and its levels can vary depending on the specific tissue or biological context in which it is expressed. The most prominent expression of MYORG is in the liver, where it is expressed at a level of around 10% of the total cellular protein. The pancreas and muscle also express MYORG at lower levels, around 5% and 2% respectively.

MYORG is a critical enzyme for the proper functioning of the body, as it helps to break down the glucose molecules that are too large to be absorbed into the bloodstream by the simple blood sugar insulin. When glucose enters the bloodstream, it is carried to the liver, where it is processed and distributed to the rest of the body.

MYORG plays a crucial role in this process, as it is the enzyme that breaks down the glucose molecules into smaller sugars that can be absorbed into the bloodstream by insulin. When glucose enters the bloodstream, it binds to theMYORG enzyme, leading to the breakdown of the glucose molecule into two smaller sugars. These smaller sugars then enter the bloodstream and are carried to the liver for further processing.

MYORG is also involved in the regulation of blood sugar levels. It helps to control the amount of glucose that enters the bloodstream, and is thereby responsible for maintaining a stable level of blood sugar. When blood sugar levels are too high, MYORG helps to break down glucose into smaller sugars and distribute them to the liver for processing. Conversely, when blood sugar levels are too low, MYORG helps to store glucose in the liver for later use.

MYORG is a target for several drugs that are currently being developed for the treatment of various diseases, including diabetes. One of the most promising drugs that is being developed for diabetes is a GLP-1 receptor agonist, which is a type of insulin secretion-promoting drug that works by mimicking the natural hormone GLP-1.

The reason why GLP-1 is such an attractive drug for diabetes is that it has been shown to be effective in improving insulin sensitivity and reducing blood sugar levels in people with type 2 diabetes. GLP-1 works by stimulating the release of insulin from the pancreas, and by inhibiting the release of other hormones that can raise blood sugar levels.

MYORG is also being targeted as a potential drug for the treatment of other diseases, including obesity and non-alcoholic fatty liver disease (NAFLD). Obesity and NAFLD are serious conditions that can lead to a range of health problems, including diabetes, heart disease, and liver damage.

MYORG has been shown to be effective in improving weight loss and reducing liver fat in obese rats, and may have similar effects in humans. It is also being investigated as a potential treatment for NAFLD, with promising results in animal models.

In conclusion, MYORG is a critical enzyme that plays a crucial role in the proper functioning of the body. It is expressed in various tissues throughout the body, including the liver, pancreas, and muscle, and is responsible for breaking down glucose molecules into smaller sugars that can be absorbed into the bloodstream by insulin.MYORG is also a target for several drugs that are currently being developed for the treatment of various diseases, including diabetes, obesity, and NAFLD. Further research is needed to fully understand the role of MYORG in these conditions, and to develop safe and effective treatments.

Protein Name: Myogenesis Regulating Glycosidase (putative)

Functions: Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2

The "MYORG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYORG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Myosin | Myosin class II | Myosin light-chain phosphatase | MYOSLID | MYOSLID-AS1 | MYOT | MYOZ1 | MYOZ2 | MYOZ3 | MYPN | MYPOP | MYRF | MYRF-AS1 | MYRFL | MYRIP | MYSM1 | MYT1 | MYT1L | MYT1L-AS1 | MYZAP | MZB1 | MZF1 | MZF1-AS1 | MZT1 | MZT2A | MZT2B | N-acetylglucosamine-1-phosphotransferase | N-CoR deacetylase complex | N-Terminal Acetyltransferase A (NatA) Complex | N-Terminal Acetyltransferase C (NatC) Complex | N-Type Calcium Channel | N4BP1 | N4BP2 | N4BP2L1 | N4BP2L2 | N4BP2L2-IT2 | N4BP3 | N6AMT1 | NAA10 | NAA11 | NAA15 | NAA16 | NAA20 | NAA25 | NAA30 | NAA35 | NAA38 | NAA40 | NAA50 | NAA60 | NAA80 | NAAA | NAALAD2 | NAALADL1 | NAALADL2 | NAALADL2-AS3 | NAB1 | NAB2 | NABP1 | NABP2 | NACA | NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK | NAGLU | NAGPA | NAGPA-AS1 | NAGS | NAIF1 | NAIP | NAIPP2 | NALCN | NALCN sodium channel complex | NALCN-AS1 | NALF1 | NALF2 | NALT1 | NAMA | NAMPT | NAMPTP1 | NANOG | NANOGNB | NANOGP1 | NANOGP8